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Guardians vs White Sox Prediction 8/7/2026 Today’s MLB Picks

Apr 29, 2026; Cleveland, Ohio, USA; Cleveland Guardians designated hitter Jose Ramirez (11) hits a double during the seventh inning against the Tampa Bay Rays at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images

Apr 29, 2026; Cleveland, Ohio, USA; Cleveland Guardians designated hitter Jose Ramirez (11) hits a double during the seventh inning against the Tampa Bay Rays at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images

MATCHUP Cleveland Guardians Chicago White Sox
Team Records 57-59 59-55
Spread -1.5 124 +1.5 -149
Moneyline -143 +119
Total Over 8.5 (-102) Under 8.5 (-119)
Where Rate Field, Chicago, Illinois
When Friday, August 7, 2026
Time 07:40 PM EDT
TV MLB.TV
In this article we will formulate a Guardians vs White Sox prediction for this MLB game on Friday, August 7th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 57-59 this season after they lost all three against the Mets by scores of 2-6, 5-6, and 6-13. In game three, Cleveland led 2-0 in the first inning, but they allowed 13 of the next 16 runs in the loss. The Guardians recorded 10 hits in the game and they were led by Lowe, who went 2-4 with one home run and three RBIs. Griffin allowed seven hits and five earned runs over 4.0 innings for the loss, while Cecconi allowed four earned runs in relief. Prior to that series, Cleveland lost two out of three against the Diamondbacks, but did win two out of three against the Reds before that. 

This season, Cleveland has a 3.82 ERA with a 1.27 WHIP and a .240 opponent batting average, while they have scored 459 runs with a .232 batting average and a .312 on base percentage. Chase DeLauter has led the Guardians with 12 home runs and 56 RBIs, while Angel Martinez has added 11 home runs and 36 RBIs. The projected starting pitcher for Cleveland is Parker Messick, who is 8-6 with a 2.57 ERA and a 1.06 WHIP over 129.2 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 59-55 this year after they lost all three against the Red Sox by scores of 2-14, 0-4, and 11-12. In game three, Chicago led 7-5 in the fifth inning, 9-7 in the 10th, 10-9 in the 11th, and 11-10 in the 12th, but couldn’t hold any lead in the loss. The White Sox recorded 13 hits and they committed one error in the game, while they were led by Meidroth, who went 3-5 with two home runs and four RBIs. Castillo allowed six hits and five earned runs over 4.0 innings, while Fedde picked up the loss in relief. Prior to that series, Chicago won two out of three against the Rays and split four games with the Yankees. 

This season, Chicago has a 4.10 ERA with a 1.31 WHIP and a .239 opponent batting average, while they have scored 544 runs with a .237 batting average and a .316 on base percentage. Colson Montgomery has led the White Sox with 25 home runs and 65 RBIs, while Miguel Vargas has added 24 home runs and 67 RBIs. The projected starting pitcher for Chicago is Noah Schultz, who is 3-8 with a 5.82 ERA and a 1.38 WHIP over 65.0 innings pitched this year. 

Why the Chicago White Sox will win

Why the Cleveland Guardians will win

Total Runs Facts

Guardians vs White Sox Prediction 

Chicago comes into this matchup after losing four of their last five games and they have scored two runs or fewer in three of those five. The White Sox are 34-21 at home this year, while the Guardians are 29-28 on the road. Cleveland has also dropped four of their last five games and they have allowed 37 runs in those four losses. The Guardians are starting Messick, who has allowed one earned run or fewer in four straight starts, while Schultz has allowed 3+ earned runs in three of his last five outings. Take the Guardians here.

David Racey's Pick: Guardians ML

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