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Diamondbacks vs Pirates Prediction 07/25/2025 Picks

Jul 22, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks designated hitter Eugenio Suarez against the Houston Astros at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

Jul 22, 2025; Phoenix, Arizona, USA; Arizona Diamondbacks designated hitter Eugenio Suarez against the Houston Astros at Chase Field. Mandatory Credit: Mark J. Rebilas-Imagn Images

MATCHUP Arizona Diamondbacks Pittsburgh Pirates
Team Records 50-53 42-61
Where PNC Park, Pittsburgh, Pennsylvania
When Friday, July 25, 2025
Time 06:40 PM EDT
TV MLB.TV

In this article we will formulate a Diamondbacks vs Pirates prediction for this MLB game on Friday, July 25th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 50-53 this season after they lost all three games against Houston by scores of 3-6, 1-3, and 3-4. In their game three loss, Arizona led 1-0 in the first inning and they tied the game in the eighth, but gave up a run in the ninth for the loss. The Diamondbacks recorded nine hits and they committed one error in the game, while they were led by Marte, who went 2-5 with one home run and one RBI in the loss. Arizona started Pfaadt, who allowed five hits and two earned runs over 5.1 innings, while Ginkel picked up the loss. 

Prior to that series, the Diamondbacks swept the Cardinals in three games, but lost two out of three against the Angels before that. Arizona has won four of their last seven games and they are currently fourth in the NL West standings. The Arizona pitching staff has a 4.58 ERA with a 1.33 WHIP and a .253 opponent batting average, while their offense has scored 522 runs with a .253 batting average and a .329 on base percentage this year. Eugenio Suarez has led Arizona with 36 home runs and 86 RBIs, while Corbin Carroll has added 21 home runs and 50 RBIs this season. The projected starting pitcher for Arizona is Ryne Nelson, who is 6-2 with a 3.52 ERA and a 1.06 WHIP over 84.1 innings pitched this season. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 42-61 this year after they swept the Tigers by scores of 3-0, 8-5, and 6-1. In their game three win, Pittsburgh scored six runs in the first three innings and they cruised to the easy victory. The Pirates recorded eight hits in the game and they were led by Horwitz, who went 1-4 with one home run and four RBIs in the win. Pittsburgh started Falter, who allowed four hits and one earned run over 7.0 innings for the win, while Mlodzinski finished the last two innings. 

Prior to that series, the Pirates lost all three against the White Sox and two out of three against the Twins. Pittsburgh has split their last six games and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.84 ERA with a 1.21 WHIP and a .236 opponent batting average, while their offense has scored 350 runs with a .232 batting average and a .301 on base percentage this season. Oneil Cruz has led Pittsburgh with 16 home runs and 40 RBIs, while Bryan Reynolds has added 10 home runs and 50 RBIs this year. The projected starting pitcher for Pittsburgh is Mike Burrows, who is 1-3 with a 4.70 ERA and a 1.41 WHIP over 46.0 innings pitched this year. 

Why the Diamondbacks will beat the Pirates

Total Runs Facts

Pittsburgh Pirates Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Diamondbacks vs Pirates Prediction 

Pittsburgh comes into this series after picking up a great sweep against the Tigers, while Arizona was on the wrong end of a sweep against Houston. The Pirates are 29-24 at home this year, while the Diamondbacks are 24-25 on the road. Arizona is one of the higher scoring teams in the MLB, but they only managed seven runs in their three games with Houston. The Diamondbacks are starting Nelson, who has allowed two earned runs or fewer in four of his last five starts. Pittsburgh is going with Burrows, who has allowed two earned runs or fewer in three of his last four outings. I think that Pittsburgh sweep of Detroit was more about how poorly the Tigers are playing right now and I think they come back to Earth here. Take Arizona. 

David Racey's Pick: Diamondbacks ML

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