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Detroit Tigers vs Cleveland Guardians Prediction 9/30/2025 Today’s MLB Picks

Sep 28, 2025; Cleveland, Ohio, USA;  Cleveland Guardians starting pitcher Slade Cecconi (44) and starting pitcher Gavin Williams, middle, celebrate after the Guardians won the American League Central Division at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images

Sep 28, 2025; Cleveland, Ohio, USA; Cleveland Guardians starting pitcher Slade Cecconi (44) and starting pitcher Gavin Williams, middle, celebrate after the Guardians won the American League Central Division at Progressive Field. Mandatory Credit: Ken Blaze-Imagn Images

MATCHUP Detroit Tigers Cleveland Guardians
Team Records 87-75 88-74
When Tuesday, September 30, 2025
Time 01:00 PM EDT
TV ESPN

The Detroit Tigers and Cleveland Guardians meet Tuesday in MLB Wild Card Game 1 at Progressive Field. Here’s a Detroit Tigers vs Cleveland Guardians Prediction. This article will include a Detroit Tigers vs Cleveland Guardians Pick.

Detroit Tigers Betting Preview

The Detroit Tigers are 87-75 on the year after playing the Guardians and Red Sox. The Detroit Tigers are batting .247 on the season, have a .316 OBP, and a .413 slugging percentage. The Detroit Tigers pitching staff has a 3.95 ERA and a 1.25 WHIP. Riley Greene leads the Detroit Tigers with 155 hits and 111 RBI, while Gleyber Torres and Spencer Torkelson have combined for 271 hits and 152 RBI.

Tarik Skubal gets the ball for the Detroit Tigers, and he is 13-6 with a 2.21 ERA and 241 strikeouts this season. Skubal is 1-1 with a 2.37 ERA and 20 strikeouts in his postseason career. Skubal is 3-3 with a 2.33 ERA and 84 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 86-73 on the year after playing the Tigers and Rangers. The Cleveland Guardians are batting .226 on the season, have a .296 OBP, and a .373 slugging percentage. The Cleveland Guardians pitching staff has a 3.70 ERA and a 1.26 WHIP. Steven Kwan leads the Cleveland Guardians with 170 hits and 56 RBI while Jose Ramirez and Kyle Manzardo have combined for 278 hits and 155 RBI.

Gavin Williams gets the ball for the Cleveland Guardians, and he is 12-5 with a 3.06 ERA and 173 strikeouts this season. Williams is 0-0 with a 11.57 ERA and 4 strikeouts in his postseason career. Williams is 3-2 with a 1.88 ERA and 55 strikeouts in his career against the Detroit Tigers.

Detroit Tigers @ Cleveland Guardians Betting Trends: September 30, 2025

Why the Cleveland Guardians will win

Why the Detroit Tigers will win

Total Runs Facts

Cleveland Guardians Player Prop Facts

Detroit Tigers Player Prop Facts

Matchup/League Facts

Detroit Tigers vs Cleveland Guardians Prediction

The Tigers are a talented team that at one point looked like the best in the league, and Skubal is one of the best arms in the sport. You can make a case for the Tigers here. However, the Tigers aren’t in great shape, winning just 3 games since September 11. Every team has a clean slate in the playoffs, but it’s hard to ignore how the Tigers are playing right now, as they went from a division winner to barely making the playoffs. The Guardians have lost just 4 games since September 5 and have won 5 of the last 6 games against the Tigers this month. Williams has allowed 22 hits and 6 runs in his last 31 innings. In 103 at bats against current Tigers, Williams is allowing a .155 batting average, .230 on base percentage and has 43 strikeouts. Give me the Guardians.

Randy Chambers's Pick: Cleveland Guardians

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