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Detroit Tigers vs Chicago White Sox Prediction 6/4/25 MLB Picks

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Chicago White Sox (19-42) vs Detroit Tigers (40-22)

Game Info: Wednesday, June 4, 2025 at 7:40 pm (Rate Field)

The Line: Betting Odds: Chicago White Sox +160 / Detroit Tigers -192 — Over/Under: 8.5

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The Detroit Tigers and the Chicago White Sox meet Wednesday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Detroit Tigers vs. Chicago White Sox prediction.

Starting Pitching Matchup

The Detroit Tigers will send out Sawyer Gipson-Long to the mound here for his first major league start since the 2023 season. The Chicago White Sox did not have a starting pitcher announced at the time that this article was posted.

Detroit Tigers Recap

The Detroit Tigers come into this game looking to rebound from their 8-1 loss at the hands of the White Sox last time out to slip to 40-22 on the year. After this series, the Tigers will head home for an interleague series against the Chicago Cubs.

Tigers Win 7 Of Their Last 9 Games

Spencer Torkelson has 48 hits along with a .235 batting average, including a team-high 14 home runs, 14 doubles, and 42 RBIs. Kerry Carpenter also has 13 home runs and 27 RBIs, while Riley Greene has 62 hits with 13 doubles, 13 home runs, and 40 RBIs, but also has a team-high 78 strikeouts this season. Dillon Dingler has 6 home runs and 24 RBIs, and Zack McKinstry’s added 10 doubles, 4 triples, 3 home runs, and 19 RBIs of his own along with 47 hits this season. Javier Baez has added 46 hits and 10 doubles as well as 6 home runs and 29 RBIs this season.

Why the Detroit Tigers will win

Detroit Tigers Player Prop Facts

Chicago White Sox Recap

The Chicago White Sox come into this game looking to build on their win over the Tigers in Tuesday’s matchup to improve to 19-42 on the year. After this series, the White Sox will square off in a division home series against the Kansas City Royals.

White Sox Snap Four-Game Losing Skid

Lenyn Sosa leads the White Sox with 55 hits, including 10 doubles and 17 RBIs. Andrew Benintendi has 29 hits, including 6 home runs, 22 RBIs, and a .242 batting average, while Miguel Vargas has a team-high 15 doubles, 8 home runs, and 26 RBIs. Brooks Baldwin has also added 16 RBIs, while Luis Robert Jr. has a team-high 21 stolen bases along with 20 RBIs so far this season. Andrew Vaughn has 5 home runs and 19 RBIs as well as 8 doubles this season.

Why the Chicago White Sox will win

Chicago White Sox Player Prop Facts

Total Runs Facts

Detroit Tigers vs. Chicago White Sox Prediction

I’m on the Tigers here. I get the case to be made for the White Sox after taking it to the Tigers on Tuesday, and Gipson-Long making his first start at this level since 2023. However, sustained success and the Chicago White Sox are not two things that have consistently gone together in recent years, and I think the Tigers take it to the White Sox once again here. Give me the Tigers in this one.

Chris Ruffolo's Pick: Detroit Tigers -192

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