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Detroit Tigers vs Chicago White Sox Prediction 9/17/2026 Today’s MLB Picks

Sep 16, 2026; Cleveland, Ohio, USA;  Chicago White Sox designated hitter Tommy Pham (21) runs the bases after hitting a three run home run off Cleveland Guardians pitcher Parker Messick (77) during there fifth inning at Progressive Field.  Mandatory Credit: David Dermer-Imagn Images

Sep 16, 2026; Cleveland, Ohio, USA; Chicago White Sox designated hitter Tommy Pham (21) runs the bases after hitting a three run home run off Cleveland Guardians pitcher Parker Messick (77) during there fifth inning at Progressive Field. Mandatory Credit: David Dermer-Imagn Images

MATCHUP Detroit Tigers Chicago White Sox
Team Records 72-80 77-75
Spread +1.5 -194 -1.5 159
Moneyline +113 -136
Total Over 8.5 (-105) Under 8.5 (-115)
Where Rate Field, Chicago, Illinois
When Thursday, September 17, 2026
Time 07:40 PM EDT
TV MLB.TV
The Detroit Tigers and Chicago White Sox meet Thursday in MLB action at Rate Field. Here’s a Detroit Tigers vs. Chicago White Sox Prediction. This article will include a Detroit Tigers vs. Chicago White Sox Pick.

Detroit Tigers Betting Preview


The Detroit Tigers are 72-80 on the year and play the Nationals and Pirates next. The Detroit Tigers are batting .239 on the season and have a .317 OBP and a .399 slugging percentage. The Detroit Tigers’ pitching staff has a 3.64 ERA and a 1.22 WHIP. Kevin McGonigle leads the Detroit Tigers with 155 hits and 65 RBI, while Dillon Dingler and Riley Greene have combined for 263 hits and 161 RBI.

Framber Valdez gets the ball for the Detroit Tigers, and he is 10-10 with a 4.01 ERA and 121 strikeouts this season. Valdez is 5–4 with a 3.25 ERA and 64 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview


The Chicago White Sox are 77-75 on the year and play the Rockies and Royals next. The Chicago White Sox are batting .235 on the season, have a .319 OBP, and have a .403 slugging percentage. The Chicago White Sox pitching staff has a 4.12 ERA and a 1.31 WHIP. Chase Meidroth leads the Chicago White Sox with 146 hits and 56 RBI, while Sam Antonacci and Miguel Vargas have combined for 261 hits and 129 RBI.

Erick Fedde gets the ball for the Chicago White Sox, and he is 8-9 with a 3.97 ERA and 91 strikeouts this season. Fedde is 0-2 with a 4.26 ERA and 19 strikeouts in his career against the Detroit Tigers.

Why the Chicago White Sox will win

Why the Detroit Tigers will win

Total Runs Facts

Chicago White Sox Player Prop Facts

Detroit Tigers Player Prop Facts

Detroit Tigers vs Chicago White Sox Prediction


Valdez has been solid in his last two starts, allowing 9 hits and 0 earned runs in his last 13 innings. However, Valdez has still been hittable all season, and he has a 4.02 ERA and a .259 allowed batting average on the road. Fedde has been more consistent, and he has a 3.13 ERA and a .248 allowed batting average at home. The White Sox are in the thick of the wild card race, and they need to take advantage of games like this if they’re going to see October baseball. The price is reasonable. Give me the White Sox, a team I’ve backed all season, and that continues to turn a profit.

Randy Chambers's Pick: Chicago White Sox

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