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Detroit Tigers vs Baltimore Orioles Prediction 5/22/2026 Today’s MLB Picks

May 20, 2026; St. Petersburg, Florida, USA; Baltimore Orioles first baseman Pete Alonso (25) hits a home run against the Tampa Bay Rays in the sixth inning at Tropicana Field. Mandatory Credit: Nathan Ray Seebeck-Imagn Images

May 20, 2026; St. Petersburg, Florida, USA; Baltimore Orioles first baseman Pete Alonso (25) hits a home run against the Tampa Bay Rays in the sixth inning at Tropicana Field. Mandatory Credit: Nathan Ray Seebeck-Imagn Images

MATCHUP Detroit Tigers Baltimore Orioles
Team Records 20-31 21-29
Spread +1.5 -179 -1.5 148
Moneyline +119 -143
Total Over 8.5 (-107) Under 8.5 (-112)
Where Oriole Park at Camden Yards, Baltimore, Maryland
When Friday, May 22, 2026
Time 07:15 PM EDT
TV Apple TV

The Detroit Tigers and Baltimore Orioles meet Friday in MLB action at Oriole Park. Here’s a Detroit Tigers vs. Baltimore Orioles Prediction. This article will include a Detroit Tigers vs. Baltimore Orioles Pick.

Detroit Tigers Betting Preview

The Detroit Tigers are 20-31 on the year and play the Angels and White Sox next. The Detroit Tigers are batting .235 on the season and have a .318 OBP, and a .372 slugging percentage. The Detroit Tigers’ pitching staff has a 3.96 ERA and a 1.28 WHIP. Riley Greene leads the Detroit Tigers with 59 hits and 24 RBI, while Dillon Dingler and Kevin McGonigle have combined for 91 hits and 45 RBI.

Jack Flaherty gets the ball for the Detroit Tigers, and he is 0-5 with a 5.77 ERA and 48 strikeouts this season. This will be Flaherty’s second career game against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 21-29 on the year and play the Rays and Blue Jays next. The Baltimore Orioles are batting .233 on the season and have a .314 OBP, and a .386 slugging percentage. The Baltimore Orioles pitching staff has a 4.97 ERA and a 1.46 WHIP. Gunnar Henderson leads the Baltimore Orioles with 46 hits and 24 RBI while Taylor Ward and Pete Alonso have combined for 88 hits and 42 RBI.

Chris Bassitt gets the ball for the Baltimore Orioles, and he is 3-3 with a 5.44 ERA and 30 strikeouts this season. Bassitt is 4-4 with a 3.88 ERA and 60 strikeouts in his career against the Detroit Tigers.

Why the Baltimore Orioles will win

Why the Detroit Tigers will win

Total Runs Facts

Baltimore Orioles Player Prop Facts

Detroit Tigers Player Prop Facts

Matchup/League Facts

Detroit Tigers vs Baltimore Orioles Prediction

Two underachieving teams riding the struggle bus and two pitchers who are in awful form. I’m looking at the over. Flaherty has a 5.77 ERA and 1.60 WHIP through 43.2 innings. Flaherty has a 5.68 ERA and a .295 allowed batting average in 19 road innings. Bassitt has a 5.44 ERA and 1.70 WHIP through 43 innings. Bassitt has allowed 16 hits and 9 runs in his last 15 innings. I expect some offense in this spot. Give me the over.

Randy Chambers's Pick: Over

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