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Cubs vs Tigers Prediction 6/6/25 MLB Picks

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Kirthmon F. Dozier / USA TODAY NETWORK

Detroit Tigers (41-23) vs Chicago Cubs (39-23)

Game Info: Friday, June 6, 2025 at 7:10 pm (Comerica Park)

The Line: Betting Odds: Detroit Tigers +205 / Chicago Cubs +172 — Over/Under: 7

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In this article, we will formulate a Cubs vs Tigers prediction for this MLB game on Friday, June 6th at Comerica Park in Detroit, Michigan. Let’s take a look at the prediction for this MLB matchup. 

Chicago Cubs Betting Preview

The Chicago Cubs are 39-23 this year after they won two out of three against Washington by scores of 8-3, 0-2, and 7-1. In their game three win, Chicago jumped out to an early lead, and they were able to pick up the easy win. The Cubs recorded 15 hits and they committed one error in the game, while they were led by Happ, who went 3-6 with one home run and four RBIs in the win. Chicago used Rea as a bulk pitcher, who allowed five hits and zero earned runs over 5.1 innings, while Thielbar, Keller, and Pressly closed out the win. 

Prior to that series, the Cubs won two out of three against the Reds and all three against the Rockies. Chicago has won eight of their last ten games, and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.71 ERA with a 1.23 WHIP and a .242 opponent batting average, while their offense has scored 356 runs with a .262 batting average and a .335 on-base percentage this season. Pete Crow-Armstrong has led Chicago with 16 home runs and 53 RBIs, while Seiya Suzuki has added 14 home runs and 53 RBIs this year. The projected starting pitcher for Chicago is Ben Brown, who is 3-3 with a 5.72 ERA and a 1.46 WHIP over 56.2 innings pitched this year. 

Detroit Tigers Betting Preview

The Detroit Tigers are 41-23 this season after they split four games with the White Sox by scores of 13-1, 1-8, 5-4, and 2-3. In their game four loss, Detroit erased a 2-0 lead in the seventh inning, but failed to score in the top of the 10th, which led to the loss. The Tigers recorded eight hits in the game, and they were led by Perez and Dingler, who both had one RBI in the loss. Detroit started Mize, who allowed six hits and two earned runs over 4.2 innings, while Brieske picked up the loss in the 10th. 

Prior to that series, the Tigers won two out of three against the Royals and swept the Giants in three games. Detroit has won eight of its last eleven games, and they are currently first in the AL Central standings. The Detroit pitching staff has a 3.19 ERA with a 1.17 WHIP and a .228 opponent batting average, while the offense has scored 317 runs with a .251 batting average and a .323 on-base percentage this season. Spencer Torkelson has led Detroit with 14 home runs and 42 RBIs, while Riley Greene has added 13 home runs and 42 RBIs this year. The projected starting pitcher for Detroit is Tarik Skubal, who is 5-2 with a 2.26 ERA and a 0.79 WHIP over 75.2 innings pitched this season. 

Why the Tigers will beat the Cubs 

Total Runs Facts

Detroit Tigers Player Prop Facts

Chicago Cubs Player Prop Facts

Cubs vs Tigers Prediction 

Detroit comes into this series after a disappointing series with the White Sox, but they continue to be the best team in the MLB. The Tigers are 21-8 at home this year, while the Cubs are 19-12 on the road. Chicago has been red hot over the last two weeks, and their offense has scored at least seven runs in three of its last four games. I trust the Chicago offense more than Detroit’s, but the Tigers are starting Skubal, who is one of the best in MLB. Take the Tigers -1.5 here. 

David Racey's Pick: Tigers -1.5

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