Cubs vs Tigers Prediction 6/6/25 MLB Picks

In this article, we will formulate a Cubs vs Tigers prediction for this MLB game on Friday, June 6th at Comerica Park in Detroit, Michigan. Let’s take a look at the prediction for this MLB matchup. 

Chicago Cubs Betting Preview

The Chicago Cubs are 39-23 this year after they won two out of three against Washington by scores of 8-3, 0-2, and 7-1. In their game three win, Chicago jumped out to an early lead, and they were able to pick up the easy win. The Cubs recorded 15 hits and they committed one error in the game, while they were led by Happ, who went 3-6 with one home run and four RBIs in the win. Chicago used Rea as a bulk pitcher, who allowed five hits and zero earned runs over 5.1 innings, while Thielbar, Keller, and Pressly closed out the win. 

Prior to that series, the Cubs won two out of three against the Reds and all three against the Rockies. Chicago has won eight of their last ten games, and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.71 ERA with a 1.23 WHIP and a .242 opponent batting average, while their offense has scored 356 runs with a .262 batting average and a .335 on-base percentage this season. Pete Crow-Armstrong has led Chicago with 16 home runs and 53 RBIs, while Seiya Suzuki has added 14 home runs and 53 RBIs this year. The projected starting pitcher for Chicago is Ben Brown, who is 3-3 with a 5.72 ERA and a 1.46 WHIP over 56.2 innings pitched this year. 

Detroit Tigers Betting Preview

The Detroit Tigers are 41-23 this season after they split four games with the White Sox by scores of 13-1, 1-8, 5-4, and 2-3. In their game four loss, Detroit erased a 2-0 lead in the seventh inning, but failed to score in the top of the 10th, which led to the loss. The Tigers recorded eight hits in the game, and they were led by Perez and Dingler, who both had one RBI in the loss. Detroit started Mize, who allowed six hits and two earned runs over 4.2 innings, while Brieske picked up the loss in the 10th. 

Prior to that series, the Tigers won two out of three against the Royals and swept the Giants in three games. Detroit has won eight of its last eleven games, and they are currently first in the AL Central standings. The Detroit pitching staff has a 3.19 ERA with a 1.17 WHIP and a .228 opponent batting average, while the offense has scored 317 runs with a .251 batting average and a .323 on-base percentage this season. Spencer Torkelson has led Detroit with 14 home runs and 42 RBIs, while Riley Greene has added 13 home runs and 42 RBIs this year. The projected starting pitcher for Detroit is Tarik Skubal, who is 5-2 with a 2.26 ERA and a 0.79 WHIP over 75.2 innings pitched this season. 

Why the Tigers will beat the Cubs 

• The Tigers have won nine of their last 10 games against National League opponents.
• The Cubs have lost four of their last five night games against AL Central opponents that held a winning record.
• The Tigers have covered the run line in each of their last five games against the Cubs following a loss.
• The Cubs have failed to cover the run line in each of their last five games against the Tigers following a win.
• The Cubs have trailed after 3 innings in three of their last four road games against opponents that held a winning record.
• The Cubs have trailed after 5 innings in four of their last five games against opponents that held a winning record.

Total Runs Facts

• Each of the Tigers’ last five home games against National League opponents have gone UNDER the total runs line.
• Each of the Cubs’ last four night games against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Cubs’ last nine road games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last four games between the Cubs and Tigers.

Detroit Tigers Player Prop Facts

• Tarik Skubal has recorded seven or more strikeouts in each of his last seven appearances against NL Central opponents.
• Colt Keith has recorded a Double in four of his last five home appearances.
• Kerry Carpenter has hit a home run in two of the Tigers’ last three games against the Cubs at Comerica Park.
• Kerry Carpenter has recorded at least one RBI in five of his six previous appearances at Comerica Park against NL Central opponents that held a winning record.
• Colt Keith has recorded at least one hit in each of his last eight appearances against opponents that held a winning record.
• Gleyber Torres has recorded at least one Single in each of his last six appearances against the Cubs after playing the previous day.
• Tarik Skubal has recorded a win in five of his last six appearances at Comerica Park against opponents that held a winning record.
• Gleyber Torres has scored a run in each of the Tigers’ last five games at Comerica Park.

Chicago Cubs Player Prop Facts

• Justin Turner has recorded at least one hit in each of his last eight road appearances against AL opponents.
• Ian Happ has recorded a Single in each of the Cubs’ last seven night games.
• Dansby Swanson has scored at least one run in each of his last seven appearances against the Tigers after playing the previous day.
• Kyle Tucker has hit a home run in each of his last three appearances against the Tigers at Comerica Park.
• Nico Hoerner has recorded an RBI in each of the Cubs’ last four games against AL Central opponents.

Cubs vs Tigers Prediction 

Detroit comes into this series after a disappointing series with the White Sox, but they continue to be the best team in the MLB. The Tigers are 21-8 at home this year, while the Cubs are 19-12 on the road. Chicago has been red hot over the last two weeks, and their offense has scored at least seven runs in three of its last four games. I trust the Chicago offense more than Detroit’s, but the Tigers are starting Skubal, who is one of the best in MLB. Take the Tigers -1.5 here.