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Cubs vs Nationals Prediction 6/4/25 MLB Picks

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Washington Nationals (28-32) vs Chicago Cubs (38-22)

Game Info: Wednesday, June 4, 2025 at 6:45 pm (Nationals Park)

The Line: Betting Odds: Washington Nationals +114 / Chicago Cubs -135 — Over/Under: 8.5

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In this article, we will formulate a Cubs vs Nationals prediction for this MLB game on Wednesday, June 4th at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

Chicago Cubs Betting Preview

The Chicago Cubs are 38-22 this season after they won game one by a score of 8-3 on Tuesday night. Chicago trailed 3-1 in the third inning, but they scored the last seven runs in the game to steal the win. The Cubs recorded nine hits in the game, and they were led by Busch, who went 3-4 with one home run and three RBIs in the win. Chicago started Horton, who allowed six hits and three earned runs over 5.1 innings for the win, while Thielbar, Cabrera, and Pressly closed out the game. 

Prior to this series, the Cubs won two out of three against the Reds and all three against the Rockies. Chicago has won seven of their last eight games, and they are currently first in the NL Central standings. The Chicago pitching staff has a 3.83 ERA with a 1.25 WHIP and a .244 opponent batting average, while their offense has scored 349 runs with a .262 batting average and a .335 on-base percentage this season. Pete Crow-Armstrong has led Chicago with 15 home runs and 51 RBIs, while Seiya Suzuki has added 14 home runs and 53 RBIs this year. The projected starting pitcher for Chicago is Matthew Boyd, who is 5-2 with a 3.08 ERA and a 1.26 WHIP over 61.1 innings pitched this season. 

Washington Nationals Betting Preview

The Washington Nationals are 28-32 this year after they dropped game one in this series on Monday night. Washington jumped out to a 3-1 lead in the third inning, but they didn’t score over the final six innings in the loss. The Nationals recorded eight hits in the game, and they were led by Abrams, Wood, and Garcia, who all had one RBI in the loss. Washington started Williams, who allowed five hits and five earned runs over 4.1 innings for the loss, while Chafin allowed two earned runs without recording an out in relief. 

Prior to this series, the Nationals won two out of three against the Diamondbacks and two out of three against the Mariners. Washington has won four of their last six games, and they are currently third in the NL East standings. The Washington pitching staff has a 5.07 ERA with a 1.39 WHIP and a .260 opponent batting average, while the offense has scored 268 runs with a .244 batting average and a .312 on-base percentage this season. James Wood has led Washington with 16 home runs and 45 RBIs, while Nathaniel Lowe has added eight home runs and 40 RBIs this year. The projected starting pitcher for Washington is MacKenzie Gore, who is 2-5 with a 3.16 ERA and a 1.20 WHIP over 68.1 innings pitched this year. 

Why the Cubs will beat the Nationals 

Total Runs Facts

Washington Nationals Player Prop Facts

Chicago Cubs Player Prop Facts

Cubs vs Nationals Prediction 

Chicago was able to record the win in game one of this series, as they continue to be one of the best teams in the MLB to start the season. The Cubs are 18-11 on the road this year, while the Nationals are 13-15 at home. Washington has hit the ball pretty well this season, but they have allowed at least seven runs in three of their last four games. The Nats are starting Gore, who has allowed two earned runs or fewer in four of his last five starts. The Cubs are going with Boyd, who has allowed two earned runs or fewer in three of his last five. This pitching matchup is pretty even, so I will take the much better offensive team at a decent price. Take the Cubs here. 

David Racey's Pick: Cubs ML

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