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Colorado Rockies vs San Diego Padres Prediction 9/14/2025 Today’s MLB Picks

Sep 13, 2025; San Diego, California, USA; San Diego Padres pitch hitter Bryce Johnson (29) flips his bat after hitting a two-run home run during the eighth inning against the Colorado Rockies at Petco Park. Mandatory Credit: David Frerker-Imagn Images

Sep 13, 2025; San Diego, California, USA; San Diego Padres pitch hitter Bryce Johnson (29) flips his bat after hitting a two-run home run during the eighth inning against the Colorado Rockies at Petco Park. Mandatory Credit: David Frerker-Imagn Images

Colorado (41-108) vs San Diego (81-68)

September 14, 2025 at 04:10 PM EDT

The Line: Betting Odds: San Diego -1.5 — Over/Under: +8.5

(Get latest betting odds)

The Colorado Rockies and San Diego Padres meet Sunday in MLB action at Petco Park. Here’s a Colorado Rockies vs San Diego Padres Prediction. This article will include a Colorado Rockies vs San Diego Padres Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 41-108 on the year and play the Marlins, Angels, and Mariners next. The Colorado Rockies are batting .239 on the season, have a .295 OBP, and a .388 slugging percentage. The Colorado Rockies pitching staff has a 5.99 ERA and a 1.59 WHIP. Hunter Goodman leads the Colorado Rockies with 135 hits and 87 RBI, while Jordan Beck and Brenton Doyle have combined for 245 hits and 106 RBI.

German Marquez gets the ball for the Colorado Rockies, and he is 3-13 with a 6.31 ERA and 77 strikeouts this season. Marquez is 11-4 with a 4.40 ERA and 119 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 81-68 on the year and play the Mets, White Sox, and Brewers next. The San Diego Padres are batting .251 on the season, have a .320 OBP, and a .387 slugging percentage. The San Diego Padres pitching staff has a 3.62 ERA and a 1.20 WHIP. Luis Arraez leads the San Diego Padres with 165 hits and 55 RBI while Manny Machado and Fernando Tatis Jr. have combined for 304 hits and 153 RBI.

Yu Darvish gets the ball for the San Diego Padres, and he is 3-5 with a 5.65 ERA and 55 strikeouts this season. Darvish is 4-4 with a 5.48 ERA and 72 strikeouts in his career against the Colorado Rockies.

Colorado Rockies @ San Diego Padres Betting Trends: September 14, 2025

  • Probable Starting Pitcher: Yu Darvish      Record this season: 3-5      ERA: 5.65
  • Home Record: 2-2
  • Last 5 against Rockies: 3-1

Why the San Diego Padres will win

  • The Rockies have lost each of their last 14 Sunday road games against NL West opponents.
  • The Padres have won eight of their last nine day games against the Rockies at Petco Park following a win.
  • The Rockies have failed to cover the run line in 10 of their last 11 games as underdogs after playing the previous day.
  • The Padres have covered the run line in seven of their last eight day games against National League opponents.
  • The Padres have won the first inning in seven of their last eight Sunday day games against National League opponents that held a losing record.
  • The Padres have led after 3 innings in each of their last five games against the Rockies at Petco Park.
  • The Rockies have trailed after 5 innings in 13 of their last 15 games as road underdogs against NL West opponents.
  • Probable Starting Pitcher: German Marquez      Record this season: 3-13      ERA: 6.31
  • Road Record: 2-5
  • Last 5 against Padres: 3-1

Why the Colorado Rockies will win

  • The Padres have lost six of their last nine games as home favorites.
  • The Padres have failed to cover the run line in each of their last four games at Petco Park following a win.
  • The road team has covered the run line in nine of the Padres’ last 12 games.

Total Runs Facts

  • Six of the Padres’ last seven games as favorites have gone UNDER the total runs line.
  • Three of the Rockies’ last four games as underdogs against the Padres have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Rockies’ last five day games against NL West opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in 11 of the Padres’ last 14 day games at Petco Park.

San Diego Padres Player Prop Facts

  • Manny Machado has hit a home run in three of the Padres’ last four games against the Rockies.
  • Yu Darvish has recorded a win in each of his last three appearances with the Padres as favorites against the Rockies.
  • Manny Machado has recorded a Double in four of the Padres’ last five day games against NL West opponents that held a losing record.
  • Luis Arraez has recorded at least one hit in 15 of his last 16 home appearances against the Rockies after playing the previous day.
  • Yu Darvish has recorded six or more strikeouts in each of his last four appearances against the Rockies.

Colorado Rockies Player Prop Facts

  • German Marquez has recorded five or more strikeouts in seven of his last eight road appearances against the Padres.
  • Brenton Doyle has hit a home run in six of his last 23 appearances against NL West opponents.
  • German Marquez has recorded a win in five of his last six appearances at Petco Park.
  • Thairo Estrada has recorded at least one hit in each of his last nine appearances against the Padres at Petco Park.

Colorado Rockies vs San Diego Padres Prediction

Another Rockies game, another chance to fade one of the worst teams in baseball history. I’ve said that a lot this season, and here they are with 108 losses. Marquez has actually had success against the Padres in his career, and Darvish hasn’t been his usual self this season. Still, we’ve been fading the Rockies all season, and there’s no reason that stops now. A $100 bettor is down more than $3000 betting the Rockies this season. Give me the Padres and the RL for max betting value.

Randy Chambers's Pick: San Diego Padres -1.5

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