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Colorado Rockies vs Chicago White Sox Prediction 9/27/2026 Today’s MLB Picks

Sep 25, 2026; Chicago, Illinois, USA;  Chicago White Sox first baseman Munetaka Murakami (5) high fives manager Will Venable (1), right, after he hit a home run during the seventh inning against the Colorado Rockies at Rate Field.  Mandatory Credit: Matt Marton-Imagn Images

Sep 25, 2026; Chicago, Illinois, USA; Chicago White Sox first baseman Munetaka Murakami (5) high fives manager Will Venable (1), right, after he hit a home run during the seventh inning against the Colorado Rockies at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Colorado Rockies Chicago White Sox
Team Records 58-103 83-78
Spread +1.5 -119 -1.5 -102
Moneyline +170 -208
Total Over 8.5 (-105) Under 8.5 (-115)
Where Rate Field, Chicago, Illinois
When Sunday, September 27, 2026
Time 03:10 PM EDT
TV MLB.TV
The Colorado Rockies and Chicago White Sox meet Sunday in MLB action at Rate Field. Here’s a Colorado Rockies vs. Chicago White Sox Prediction. This article will include a Colorado Rockies vs. Chicago White Sox Pick.

Colorado Rockies Betting Preview 


The Colorado Rockies are 58-103 on the year. The Colorado Rockies are batting .254 on the season and have a .323 OBP and a .417 slugging percentage. The Colorado Rockies’ pitching staff has a 5.59 ERA and a 1.53 WHIP. TJ Rumfield leads the Colorado Rockies with 161 hits and 71 RBI, while Jake McCarthy and Hunter Goodman have combined for 282 hits and 167 RBI.

Kyle Freeland gets the ball for the Colorado Rockies, and he is 4-11 with a 6.58 ERA and 106 strikeouts this season. Freeland is 3-0 with a 2.03 ERA and 23 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview 


The Chicago White Sox are 83-78 on the season. The Chicago White Sox are batting .236 on the season, have a .321 OBP, and have a .404 slugging percentage. The Chicago White Sox pitching staff has a 4.13 ERA and a 1.32 WHIP. Chase Meidroth leads the Chicago White Sox with 155 hits and 63 RBI, while Sam Antonacci and Miguel Vargas have combined for 274 hits and 140 RBI.

Anthony Kay gets the ball for the Chicago White Sox, and he is 9-9 with a 4.53 ERA and 125 strikeouts this season. This will be Kay’s first career game against the Colorado Rockies.

Why the Chicago White Sox will win

Why the Colorado Rockies will win

Total Runs Facts

Chicago White Sox Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Colorado Rockies vs Chicago White Sox Prediction


The White Sox don’t have anything to play for, but they should still win at home. The Rockies suck, and Freeland is rocking a 6.58 ERA and 1.52 WHIP through 131.1 innings. I’ve been on the White Sox all season, and they’re the third most profitable team in baseball. Only the Rays and Brewers have earned more money this season than the White Sox. I’ll back the White Sox again and lay the RL to shave down the price.

Randy Chambers's Pick: Chicago White Sox -1.5

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