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Colorado Rockies vs Chicago White Sox Prediction 9/25/2026 Today’s MLB Picks

Aug 26, 2026; Chicago, Illinois, USA;  Chicago White Sox pitcher Sean Burke (59) delivers the ball during the first inning against the Texas Rangers at Rate Field.  Mandatory Credit: Matt Marton-Imagn Images

Aug 26, 2026; Chicago, Illinois, USA; Chicago White Sox pitcher Sean Burke (59) delivers the ball during the first inning against the Texas Rangers at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Colorado Rockies Chicago White Sox
Team Records 57-102 82-77
Spread +1.5 -114 -1.5 -106
Moneyline +187 -230
Total Over 8 (-115) Under 8 (-105)
Where Rate Field, Chicago, Illinois
When Friday, September 25, 2026
Time 07:40 PM EDT
TV MLB.TV
In this article, we will formulate a Rockies vs White Sox Prediction for this MLB matchup on Friday, September 25th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview


The Chicago White Sox have a 82-77 record this season and are sitting in the 2nd place of the AL Central. They have a 46-32 home record and are coming off a 1-9 road loss against the Royals.

The Chicago White Sox have a .236 batting average this season, .321 OBP and .404 Slugging percentage. Chicago’s pitching staff has a 4.13 ERA and 1.32 WHIP. Chase Meidroth is the team’s best hitter with a .275 batting average. Miguel Vargas leads the team in RBI with 92, adding a team-high 33 home runs.

Sean Burke (R) is the projected starting pitcher for the White Sox, and he has a 10-7 record, 3.40 ERA and 1.20 WHIP.

Colorado Rockies Preview


The Colorado Rockies have a 57-102 record this season and are sitting in the 5th place of the NL West. They have a 25-53 away record and are coming off an 8-12 home loss against the Diamondbacks.

The Colorado Rockies have a .254 batting average this season, .323 OBP and .417 Slugging percentage. Colorado’s pitching staff has a 5.59 ERA and 1.53 WHIP. TJ Rumfield is the team’s best hitter with a .297 batting average. Hunter Goodman leads the team in RBI with 84, adding a team-high 39 home runs.

Tomoyuki Sugano (R) is the projected starting pitcher for the Rockies, and he has a 12-11 record, 5.36 ERA and 1.33 WHIP.

Colorado Rockies @ the Chicago White Sox Betting Trends: September 25, 2026


Why the Chicago White Sox will win

Why the Colorado Rockies will win

Total Runs Facts

Chicago White Sox Player Prop Facts

Colorado Rockies Player Prop Facts

Matchup/League Facts

Rockies vs White Sox Prediction


Both teams are tied 5-5 in their last 10 meetings and the Reds are 3-1 in their last 4 visits in Toronto.

In this Rockies vs White Sox Prediction, the Blue Jays are coming as -225 home favorites. The White Sox are playing for the NL Central title and have been in excellent form, with a 4-1 record in their last 5 games, having scored 8+ runs in three of their last four games. They also have the best pitcher on the mound, as Sean Burke goes up against a struggling Tomoyuki Sugano, who has given up 5+ runs in five of his last seven starts. Take the White Sox to win this one comfortably and cover the ruline.

Nikos Lagouretos's Pick: Chicago White Sox -1.5

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