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Cleveland Guardians vs Seattle Mariners Prediction 3/26/2026 Today’s MLB Picks

Oct 19, 2025; Toronto, Ontario, CAN; Seattle Mariners pitcher Logan Gilbert (36) throws in the first inning against the Toronto Blue Jays during game six of the ALCS round for the 2025 MLB playoffs at Rogers Centre. Mandatory Credit: Nick Turchiaro-Imagn Images

Oct 19, 2025; Toronto, Ontario, CAN; Seattle Mariners pitcher Logan Gilbert (36) throws in the first inning against the Toronto Blue Jays during game six of the ALCS round for the 2025 MLB playoffs at Rogers Centre. Mandatory Credit: Nick Turchiaro-Imagn Images

MATCHUP Cleveland Guardians Seattle Mariners
Team Records 0-0 0-0
Spread +1.5 -149 -1.5 123
Moneyline +159 -193
Total Over 6.5 (-122) Under 6.5 (102)
Where T-Mobile Park, Seattle, Washington
When Thursday, March 26, 2026
Time 10:10 PM EDT
TV MLB.TV
In this article, we will formulate a Guardians vs Mariners Prediction for this MLB matchup on Thursday, March 26th. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview


The Seattle Mariners finished last season with a 90-72 record and were placed 1st in the AL West. They had a 51-30 home record and 39-42 away record and were 96-72-6 in over/under.

Last season the Mariners had a .244 batting average, .320 OBP and .420 Slugging percentage. Seattle’s pitching staff had a 3.87 ERA and 1.22 WHIP. Julio Rodríguez led the Mariners with 174 hits. Dominic Canzone was the team’s best hitter with a .300 batting average. Cal Raleigh led the team in RBI, with 125 and added a team-high 47 home runs.

Logan Gilbert (R) is the projected starting pitcher for the Mariners, and last season he had a 6-6 record, 3.44 ERA and 1.03 WHIP.

Cleveland Guardians Preview


The Cleveland Guardians finished last season with an 88-74 record and were placed 1st in the AL Central. They had a 45-36 home record and 43-38 away record and were 72-86-7 in over/under.

Last season the Guardians had a .226 batting average, .296 OBP and .373 Slugging percentage. Cleveland’s pitching staff had a 3.70 ERA and 1.26 WHIP. Steven Kwan led the Guardians with 170 hits. José Ramírez was the team’s best hitter with a .283 batting average. José Ramírez also led the team in RBI, with 85 and added a team-high 30 home runs.

Tanner Bibee (R) is the projected starting pitcher for the Guardians, and last season he had a 12-11 record, 4.24 ERA and 1.23 WHIP.

Cleveland Guardians @ Seattle Mariners Betting Trends: March 26, 2026


Why the Seattle Mariners will win


Why the Cleveland Guardians will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Cleveland Guardians Player Prop Facts

Guardians vs Mariners Prediction


The Mariners were 4-2 in their six meetings against the Guardians last season, sweeping their only series in Seattle by 3-0 wins. Over is 7-3 in their last 10 meetings.  

In this Guardians vs Mariners Prediction, the Mariners are coming as -170 home favorites. Both teams were very good last season and Seattle made it all the way to the ALCS Finals where they lost to Toronto. Cleveland had the third-best bullpen in the league last season but they were also the second-worst hitting team against right-handed pitching. Bibee has also been significantly weaker on the road for the Guardians with a 5.17 road ERA, while Gilbert has been excellent last season and elite at home with a 2.24 home ERA. Take the Mariners to win their season opener in front of their home crowd.

Nikos Lagouretos's Pick: Seattle Mariners ML

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