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Cleveland Guardians vs Minnesota Twins Prediction 5/19/25 MLB Picks

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Minnesota Twins (26-21) vs Cleveland Guardians (25-21)

Game Info: Monday, May 19, 2025 at 7:40 pm (Target Field)

The Line: Betting Odds: Minnesota Twins -135 / Cleveland Guardians +114 — Over/Under: 7.5

(Get latest betting odds)

The Cleveland Guardians and Minnesota Twins meet Monday in MLB action at Target Field. Here’s a Cleveland Guardians vs Minnesota Twins Prediction. This article will include a Cleveland Guardians vs Minnesota Twins Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 25-21 on the year and play the Tigers, Dodgers, and Angels next. The Cleveland Guardians are batting .233 on the season, have a .307 OBP, and a .380 slugging percentage. The Cleveland Guardians’ pitching staff has a 4.14 ERA and a 1.41 WHIP. Steven Kwan leads the Cleveland Guardians with 56 hits and 17 RBI, while Jose Ramirez and Gabriel Arias have combined for 85 hits and 42 RBI. 

Logan Allen gets the ball for the Cleveland Guardians, and he is 2-2 with a 3.70 ERA and 31 strikeouts this season. Allen is 2-0 with a 2.04 ERA and 14 strikeouts in his career against the Minnesota Twins.

Minnesota Twins Betting Preview

The Minnesota Twins are 26-21 on the year and play the Royals, Rays, and Mariners next. The Minnesota Twins are batting .242 on the season, have a .310 OBP, and a .386 slugging percentage. The Minnesota Twins pitching staff has a 3.20 ERA and a 1.14 WHIP. Ty France leads the Minnesota Twins with 42 hits and 23 RBI, while Trevor Larnach and Byron Buxton have combined for 83 hits and 50 RBI.

Bailey Ober gets the ball for the Minnesota Twins, and he is 4-1 with a 3.72 ERA and 40 strikeouts this season. Ober is 3-2 with a 2.05 ERA and 48 strikeouts in his career against the Cleveland Guardians.

Why the Minnesota Twins will win

Why the Cleveland Guardians will win

Minnesota Twins Player Prop Facts

Cleveland Guardians Player Prop Facts

Cleveland Guardians vs Minnesota Twins Prediction

The Guardians are coming off a rough week, which includes four straight losses and an offense that can’t produce consistently. So, while Allen has been strong this season, which includes five earned runs in his last 15.2 innings, it’s hard to take the Guardians seriously during this streak. The Twins have lost one game since May 3 and are absolutely dealing pitching-wise. Ober has allowed five earned runs in his last 15.2 innings, and he has a 2.53 ERA in 21.1 home innings. I’m not stepping in front of the Twins as long as the tickets keep cashing.

Randy Chambers's Pick: Minnesota Twins -135

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