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Cleveland Guardians vs Kansas City Royals Prediction 9/26/2026 Today’s MLB Picks

Sep 24, 2026; Kansas City, Missouri, USA;  Kansas City Royals third baseman Nick Loftin (12) throws to first base during the sixth inning against the Chicago White Sox at Kauffman Stadium.  Mandatory Credit: William Purnell-Imagn Images

Sep 24, 2026; Kansas City, Missouri, USA; Kansas City Royals third baseman Nick Loftin (12) throws to first base during the sixth inning against the Chicago White Sox at Kauffman Stadium. Mandatory Credit: William Purnell-Imagn Images

MATCHUP Cleveland Guardians Kansas City Royals
Team Records 84-76 68-92
Spread -1.5 128 +1.5 -155
Moneyline -131 +109
Total Over 8.5 (-107) Under 8.5 (-112)
Where Kauffman Stadium, Kansas City, Missouri
When Saturday, September 26, 2026
Time 07:10 PM EDT
TV MLB.TV
The Cleveland Guardians and Kansas City Royals meet Saturday in MLB action at Kauffman Stadium. Here’s a Cleveland Guardians vs. Kansas City Royals Prediction. This article will include a Cleveland Guardians vs Kansas City Royals Pick.

Cleveland Guardians Betting Preview


The Cleveland Guardians are 84-76 on the season. The Cleveland Guardians are batting .238 on the season, have a .315 OBP, and a .376 slugging percentage. The Cleveland Guardians pitching staff has a 3.76 ERA and a 1.26 WHIP. Steven Kwan leads the Cleveland Guardians with 149 hits and 31 RBI, while Chase DeLauter and Brayan Rocchio have combined for 273 hits and 137 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 6-15 with a 4.35 ERA and 142 strikeouts this season. Bibee is 4-2 with a 3.32 ERA and 52 strikeouts in his career against the Kansas City Royals.

Kansas City Royals Betting Preview


The Kansas City Royals are 68-92 on the year. The Kansas City Royals are batting .247 on the season, have a .316 OBP, and have a .401 slugging percentage. The Kansas City Royals’ pitching staff has a 4.77 ERA and a 1.41 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 155 hits and 54 RBI, while Salvador Perez and Jac Caglianone have combined for 275 hits and 150 RBI.

Michael Wacha gets the ball for the Kansas City Royals, and he is 9-9 with a 3.33 ERA and 154 strikeouts this season. Wacha is 5-2 with a 2.07 ERA and 57 strikeouts in his career against the Cleveland Guardians.

Why the Kansas City Royals will win

Why the Cleveland Guardians will win

Total Runs Facts

Kansas City Royals Player Prop Facts

Cleveland Guardians Player Prop Facts

Cleveland Guardians vs Kansas City Royals Prediction


The Guardians are obviously the better team, and Bibee isn’t a terrible option. We’ve also made a killing fading the Royals all season. However, we’re getting plus money with Wacha on the mound, an all-star who has a 3.33 ERA and 1.11 WHIP. At home through 89 innings, Wacha has a 2.93 ERA and a .210 allowed batting average. Yes, the Guardians are fighting for a division crown, but I still like the more favorable price with a quality arm on the mound.

Randy Chambers's Pick: Kansas City Royals

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