Cleveland Guardians vs Chicago White Sox Prediction 8/8/2026 Today’s MLB Picks
Chris Ruffolo
Jul 31, 2026; St. Petersburg, Florida, USA; Chicago White Sox first baseman Munetaka Murakami (5) runs the bases after hitting a two-run home run against the Tampa Bay Rays in the third inning at Tropicana Field. Mandatory Credit: Nathan Ray Seebeck-Imagn Images
MATCHUP
Cleveland Guardians
Chicago White Sox
Team Records
58-59
59-56
Spread
-1.5 133
+1.5 -161
Moneyline
-124
+116
Total
Over 7.5 (-102)
Under 7.5 (-118)
Where
Rate Field, Chicago, Illinois
When
Saturday, August 8, 2026
Time
07:15 PM EDT
TV
MLB.TV
The Cleveland Guardians and the Chicago White Sox meet Saturday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs. Chicago White Sox prediction.
Starting Pitching Matchup
The Cleveland Guardians will send out Gavin Williams for the start here and Williams is 11-6 with a 3.56 ERA and 178 strikeouts this season. Anthony Kay will start for the White Sox here and is 8-5 with a 4.01 ERA and 90 strikeouts this season.
Cleveland Guardians Recap
The Cleveland Guardians come into this game looking to add on to their 8-2 win over the White Sox on Friday to sit at 58-59 this season. After this series, the Guardians will head on the road for a series against the Detroit Tigers.
Guardians Snap Three-Game Slide
Chase DeLauter has 102 hits with 21 doubles, 12 home runs and 56 RBIs while Steven Kwan has 94 hits with 14 doubles, a home run and 21 RBIs and Jose Ramirez has 73 hits with 18 doubles, 10 home runs and 35 RBIs this season. Brayan Rocchio has also added 101 hits with 17 doubles, 9 home runs and 50 RBIs this season while Angel Martinez has 59 hits with 13 doubles, 11 homers and 36 RBIs and Rhys Hoskins has added 43 hits with 13 doubles, 12 home runs and 36 RBIs. Daniel Schneemann has 52 hits with 11 doubles, 6 home runs and 28 RBIs this season.
Chicago White Sox Recap
The Chicago White Sox come into this game looking to bounce back from their loss at the hands of Cleveland on Friday to sit at 59-56 this season. After this series, the White Sox will take on the Cincinnati Reds in a set at home.
White Sox Drop 4th In A Row
Munetaka Murakami has 67 hits with 24 home runs and 51 RBIs while Miguel Vargas has 99 hits with 25 doubles, a triple, 24 home runs and 67 RBIs and Colson Montgomery has 88 hits with 18 doubles, 25 home runs and 65 RBIs. Luisangel Acuna has 41 hits and Tristan Peters has 81 hits with 21 doubles and 38 RBIs so far this season. Chase Meidroth also has 112 hits with 20 doubles, 11 home runs and 44 RBIs this year.
Cleveland Guardians @ the Chicago White Sox Betting Trends: August 8, 2026
Probable Starting Pitcher: Anthony Kay Record this season: 8-5 ERA: 4.01
Home Record: 5-3
Last 5 against Guardians: 0-0
Why the Chicago White Sox will win
The Guardians have lost each of their last four games as favorites following a win.
The underdogs have won three of the Guardians’ last four games.
The Guardians have failed to cover the run line in 11 of their last 12 games as favorites against American League opponents following a win.
The White Sox have covered the run line in eight of their last nine games against the Guardians.
The Guardians have trailed after 3 innings in three of their last four games.
The Guardians have trailed after 5 innings in three of their last four road games against opponents that held a winning record.
Probable Starting Pitcher: Gavin Williams Record this season: 11-6 ERA: 3.56
Road Record: 6-4
Last 5 against White Sox: 1-1
Why the Cleveland Guardians will win
The Guardians have won each of their last nine night games against AL Central opponents following a road win.
The White Sox have lost each of their last four games.
The road team has covered the run line in seven of the Guardians’ last eight games.
The White Sox have failed to cover the run line in four of their last five home games against AL Central opponents that held a losing record.
The Guardians have won the first inning in each of their last three night games against opponents that held a winning record.
The Guardians have led after 3 innings in each of their last four games against opponents that held a winning record.
The White Sox have trailed after 5 innings in five of their last six games as home underdogs.
Total Runs Facts
Seven of the Guardians’ last eight games as road favorites have gone UNDER the total runs line.
Four of the White Sox’s last five games have gone OVER the total runs line.
There has been no run scored during the first inning in nine of the Guardians’ last 10 road games against AL Central opponents.
There has been no run scored during the first inning in five of Anthony Kay’s last six appearances as a starter.
Chicago White Sox Player Prop Facts
Munetaka Murakami has hit a home run in three of his last four appearances in night games against AL Central teams that held a losing record.
Anthony Kay has recorded a win in four of his last five appearances against AL Central opponents that held a losing record.
Anthony Kay has recorded four or more strikeouts in each of his last four appearances in night games against teams that held a losing record.
Randal Grichuk has recorded at least one hit in each of his last 12 home appearances against the Guardians.
Cleveland Guardians Player Prop Facts
Gavin Williams has recorded a win in four of his last five road appearances against AL Central opponents that held a winning record.
Gavin Williams has recorded 10+ strikeouts in each of his last five appearances.
Steven Kwan has recorded at least one hit in each of his last 18 appearances against opponents that held a winning record.
Patrick Bailey has hit a home run in three of his last four appearances against AL Central opponents.
Gavin Williams ranks 3rd in the league for total Strikeouts (178) this season.
Matchup/League Facts
The White Sox rank T6th in the league for home runs this season (150).
The White Sox rank 25th in the league for strikeouts against this season (1050).
The Guardians rank 30th in the league for slugging percentage this season (.369).
The Guardians rank 28th in the league for runs scored this season (467).
Cleveland Guardians vs. Chicago White Sox Prediction
I’m on the under in this game. I just think this ends up being a bit of a pitcher’s duel here, as Williams is on a strikeout tear right now and Anthony Kay has been much stronger at home so far this season. I think this ends up being a low-scoring game so give me the under.