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Cincinnati Reds vs Toronto Blue Jays Prediction 9/25/2026 Today’s MLB Picks

Sep 14, 2026; Toronto, Ontario, CAN;  Toronto Blue Jays starting pitcher Jose Soriano (40) pitches to the Detroit Tigers during the third inning at Rogers Centre.  Mandatory Credit: John E. Sokolowski-Imagn Images

Sep 14, 2026; Toronto, Ontario, CAN; Toronto Blue Jays starting pitcher Jose Soriano (40) pitches to the Detroit Tigers during the third inning at Rogers Centre. Mandatory Credit: John E. Sokolowski-Imagn Images

MATCHUP Cincinnati Reds Toronto Blue Jays
Team Records 74-85 77-82
Spread +1.5 -198 -1.5 162
Moneyline +113 -136
Total Over 7.5 (-112) Under 7.5 (-108)
Where Rogers Centre, Toronto, Ontario
When Friday, September 25, 2026
Time 07:07 PM EDT
TV MLB.TV
In this article, we will formulate a Reds vs Blue Jays Prediction for this MLB matchup on Friday, September 25th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Toronto Blue Jays Preview


The Toronto Blue Jays have a 77-82 record this season and are sitting in the 5th place of the AL East. They have a 40-38 home record and are coming off a 2-4 road loss against the Orioles.

The Toronto Blue Jays have a .248 batting average this season, .310 OBP and .382 Slugging percentage. Toronto’s pitching staff has a 3.92 ERA and 1.30 WHIP. Ernie Clement is the team’s best hitter with a .264 batting average. Kazuma Okamoto leads the team in RBI with 89, adding a team-high 33 home runs.

Jose Soriano (R) is the projected starting pitcher for the Blue Jays, and he has a 12-8 record, 3.72 ERA and 1.26 WHIP.

Cincinnati Reds Preview


The Cincinnati Reds have a 74-85 record this season and are sitting in the 5th place of the NL Central. They have a 36-42 away record and are coming off a 7-6 road win against the Braves.

The Cincinnati Reds have a .228 batting average this season, .305 OBP and .395 Slugging percentage. Cincinnati’s pitching staff has a 4.85 ERA and 1.45 WHIP. Elly De La Cruz is the team’s best hitter with a .285 batting average. Sal Stewart leads the team in RBI with 110, adding a team-high 32 home runs.

Nick Lodolo (L) is the projected starting pitcher for the Reds, and he has a 3-6 record, 5.04 ERA and 1.47 WHIP.

Cincinnati Reds @ Toronto Blue Jays Betting Trends: September 25, 2026


Why the Toronto Blue Jays will win

Why the Cincinnati Reds will win

Total Runs Facts

Toronto Blue Jays Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Reds vs Blue Jays Prediction


Both teams are tied 5-5 in their last 10 meetings and the Reds are 3-1 in their last 4 visits in Toronto.

In this Reds vs Blue Jays Prediction, the Blue Jays are coming as -135 home favorites. Both teams have nothing to play for and I like the Jays at home in this one. Soriano has been in bad shape, but Lodolo has been even worse, sitting on a 5.97 road ERA. On top of that, Toronto has a better bullpen and Cincinnati’s bats have been struggling lately, averaging just 3.1 runs per game in their last 10. Take the Blue Jays to win.

Nikos Lagouretos's Pick: Toronto Blue Jays ML

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