Cincinnati Reds vs St. Louis Cardinals Prediction 7/24/2026 Today’s MLB Picks

The Cincinnati Reds and the St. Louis Cardinals meet Friday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. St. Louis Cardinals prediction.

Starting Pitching Matchup

The Cincinnati Reds will send out Rhett Lowder for the start here and Lowder is 3-7 with a 5.75 ERA and 61 strikeouts this season. Dustin May will start this one for St. Louis and is 5-7 with a 4.78 ERA and 95 strikeouts this season. 

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to add on to their 5-3 win over the Seattle Mariners last time out to sit at 47-54 this season. After this series, the Reds will head home for a series against the Cleveland Guardians.

Reds Win Back-To-Back Games

Elly De La Cruz has 90 hits with 15 doubles, 4 triples, 17 home runs and 46 RBIs while Sal Stewart has 96 hits with 23 doubles, 21 home runs and 74 RBIs. Spencer Steer has 81 hits with 14 doubles, 16 home runs and 40 RBIs and Matt McLain has 51 hits with 13 doubles, 8 home runs and 25 RBIs. JJ Bleday’s added 62 hits with 11 doubles, 17 home runs and 44 RBIs as well on the year.

St. Louis Cardinals Recap

The St. Louis Cardinals come into this game looking to bounce back from a 10-6 loss at the hands of the Arizona Diamondbacks last time out to sit at 52-50 this season. After this series, the Cardinals will take on the Chicago Cubs in a series at home.

Cardinals Lose 5 Of Last 6

Jordan Walker leads the Cardinals with 112 hits, 22 doubles, 22 home runs and 77 RBIs while Alec Burleson has 110 hits with 25 doubles, 15 home runs and 69 RBIs. JJ Wetherholt has 99 hits with 15 home runs and 40 RBIs while Ivan Herrera has 90 hits with 14 doubles, 11 home runs and 41 RBIs. Nolan Gorman has 39 hits with 7 home runs and 26 RBIs this season. Masyn Winn’s added 80 hits with 12 doubles and 42 RBIs and Nathan Church has 59 hits with 8 home runs and 29 RBIs this season. 

Cincinnati Reds @ St. Louis Cardinals Betting Trends: July 24, 2026

• Probable Starting Pitcher: Dustin May      Record this season: 5-7      ERA: 4.78
• Home Record: 3-3
• Last 5 against Reds: –

Why the St. Louis Cardinals will win

• The Reds have lost each of their last six night games following a win.
• The Cardinals have won seven of their last eight night games against the Reds at Busch Stadium following a home loss.
• The Cardinals have covered the run line in seven of their last eight games against National League opponents following a loss.
• The Reds have failed to cover the run line in four of their last five road games against NL Central opponents.
• The Cardinals have led after 3 innings in each of their last three games against National League opponents that held a losing record.
• The Cardinals have won the first inning in each of their last three home games.
• The Cardinals have led after 5 innings in each of their last three night games against National League opponents that held a losing record.

• Probable Starting Pitcher: Rhett Lowder      Record this season: 3-7      ERA: 5.75
• Road Record: 2-6
• Last 5 against Cardinals: 1-0

Why the Cincinnati Reds will win

• The Cardinals have lost four of their last five games as favorites.
• The Reds have won four of their last five games as road underdogs.
• The Cardinals have failed to cover the run line in 12 of their last 13 games as favorites after playing the previous day.
• The Reds have covered the run line in seven of their last eight games as underdogs against the Cardinals following a win.
• The Reds have won the first inning in four of their last five road games against opponents that held a winning record.
• The Cardinals have trailed after 5 innings in four of their last five home games.
• The Reds have led after 3 innings in three of their last four games against National League opponents.

Total Runs Facts

• Nine of the Reds’ last 10 night games as underdogs have gone UNDER the total runs line.
• Each of the Cardinals’ last four night games after playing the previous day have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in each of the Reds’ last seven road games against National League opponents.
• There has been no run scored during the first inning in four of the last five games between the Reds and Cardinals.

St. Louis Cardinals Player Prop Facts

• Alec Burleson has hit a home run in each of the Cardinals’ last three games against NL opponents that held a losing record.
• Dustin May has recorded seven or more strikeouts in four of his last five home appearances.
• Ivan Herrera has recorded at least one hit in each of the Cardinals’ last nine Friday games against opponents that held a losing record.
• Jordan Walker ranks 8th in the league in Hits (112) this season.

Cincinnati Reds Player Prop Facts

• Eugenio Suarez has hit a home run in each of the Reds’ last three games against opponents that held a winning record.
• Rhett Lowder has recorded four or more strikeouts in five of his last six appearances with the Reds as underdogs.
• Tyler Stephenson has recorded at least one hit in each of his last 15 road appearances against NL opponents.
• Elly De La Cruz is one of only seven players to record 10+ Home Runs and 4+ Triples this season.

Matchup/League Facts

• The Cardinals rank T2nd in the league for home runs allowed this season (101).
• The Cardinals rank T2nd in the league for home runs allowed this season (101).
• The Reds rank 30th in the league for hits this season (777).
• The Reds rank 30th in the league for hits this season (777).

Cincinnati Reds vs. St. Louis Cardinals Prediction

I’m on the over in this one as I think the starting pitching matchup is just primed to produce runs. Rhett Lowder’s struggled wherever he’s been this season and Dustin May can be hit or miss, but the Reds found some offense in that series against the Mariners and I think that carries over in a high-scoring opener on Friday. Give me the over.

Chris Ruffolo's Pick: Over 8.5