Cincinnati Reds vs St. Louis Cardinals Prediction 6/7/2026 Today’s MLB Picks
Chris Ruffolo
Jun 6, 2026; St. Louis, Missouri, USA; St. Louis Cardinals right fielder Jordan Walker (18) hits a solo home run against the Cincinnati Reds during the fifth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images
MATCHUP
Cincinnati Reds
St. Louis Cardinals
Team Records
31-32
34-28
Spread
+1.5 -162
-1.5 134
Moneyline
+129
-156
Total
Over 9.5 (100)
Under 9.5 (-120)
Where
Busch Stadium, St. Louis, Missouri
When
Sunday, June 7, 2026
Time
02:15 PM EDT
TV
MLB.TV
The Cincinnati Reds and the St. Louis Cardinals meet Sunday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. St. Louis Cardinals prediction.
Starting Pitching Matchup
The Cincinnati Reds will send out Rhett Lowder for the start here and Lowder is 3-3 with a 5.40 ERA and 27 strikeouts this season. This will be Lowder’s second career start against the Cardinals. Michael McGreevy will start for the Cardinals here and is 3-5 with a 2.98 ERA and 44 strikeouts this season. In his career, McGreevy is 2-0 with a 0.69 ERA and 6 strikeouts against the Reds.
Cincinnati Reds Recap
The Cincinnati Reds will be out to bounce back from their 6-5 loss at the hands of the Cardinals on Saturday to sit at 31-32 this season. After this series, the Reds will head on the road again for a series against the San Diego Padres.
Reds Lose 7 Of Last 9
Going into Saturday, Elly De La Cruz has 65 hits with 13 doubles, 2 triples, 12 home runs and 37 RBIs while Sal Stewart has 61 hits with 13 doubles, 12 home runs and 39 RBIs. Spencer Steer has 58 hits with 12 doubles, 9 home runs and 23 RBIs and Matt McLain has 40 hits with 10 doubles, 5 home runs and 21 RBIs. JJ Bleday’s added 26 hits with 8 doubles, 10 home runs and 27 RBIs as well on the year.
St. Louis Cardinals Recap
The St. Louis Cardinals come into this game looking to add on to their win over the Reds from Saturday to sit at 34-28 this season. After this series, the Cardinals will head on the road for a series against the New York Mets.
Cardinals Win 3 In A Row
Entering Saturday, Jordan Walker leads the Cardinals with 69 hits, 13 doubles, 15 home runs and 45 RBIs while Alec Burleson has 68 hits with 15 doubles, 8 home runs and 43 RBIs. JJ Wetherholt has 56 hits with 9 home runs and 25 RBIs while Ivan Herrera has 59 hits with 12 doubles, 7 home runs and 28 RBIs. Nolan Gorman has 39 hits with 7 home runs and 26 RBIs this season. Masyn Winn’s added 47 hits with 8 doubles and 22 RBIs and Nathan Church has 36 hits with 5 home runs and 18 RBIs this season.
Cincinnati Reds @ St. Louis Cardinals Betting Trends: June 7, 2026
Probable Starting Pitcher: Michael McGreevy Record this season: 3-5 ERA: 2.98
Home Record: 1-2
Last 5 against Reds: 2-0
Why the St. Louis Cardinals will win
The Reds have lost each of their last 10 road games against NL Central opponents.
The favorites have won each of the Cardinals’ last seven games.
The Reds have failed to cover the run line in four of their last five games.
The Cardinals have covered the run line in three of their last four games as favorites.
The Cardinals have led after 3 innings in three of their last four day games against opponents that held a losing record.
The Cardinals have led after 5 innings in three of their last four games as favorites.
Probable Starting Pitcher: Rhett Lowder Record this season: 3-3 ERA: 5.40
Road Record: 2-3
Last 5 against Cardinals: 1-0
Why the Cincinnati Reds will win
The Cardinals have lost 13 of their last 18 games as favorites against National League opponents following a win.
The Reds have won six of their last seven Sunday games as underdogs against the Cardinals.
The Cardinals have failed to cover the run line in 14 of their last 15 games as favorites against National League opponents following a home win.
The Reds have covered the run line in each of their last six day games against the Cardinals following a loss.
The Cardinals have trailed after 5 innings in each of their last four day games at Busch Stadium against National League opponents.
Total Runs Facts
Each of the Cardinals’ last five games as favorites against the Reds have gone OVER the total runs line.
Each of the Reds’ last five games as underdogs against NL Central opponents have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of Michael McGreevy’s last eight appearances as a starter.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last four day games against NL Central opponents.
St. Louis Cardinals Player Prop Facts
Alec Burleson has hit a home run in two of the Cardinals’ last three home games against the Reds.
Masyn Winn has recorded at least one hit in each of his last six home appearances against the Reds after playing the previous day.
Jordan Walker is one of only three players to hit over .300 and have 45+ RBIs this season.
Cincinnati Reds Player Prop Facts
JJ Bleday has recorded at least one hit in each of the Reds’ last eight road games against NL Central opponents.
Elly De La Cruz has hit a home run in two of his last three appearances with the Reds as underdogs against the Cardinals.
Sal Stewart is one of only nine players to record 10+ Home Runs and 10+ Stolen Bases this season.
Matchup/League Facts
The Cardinals rank T28th in the league for triples this season (5).
The Cardinals rank 27th in the league for strikeouts this season (478).
The Reds rank 28th in the league for hits this season (486).
The Reds rank 28th in the league for walks allowed this season (290).
Cincinnati Reds vs. St. Louis Cardinals Prediction
I’m backing the over in this one. I get the case to be made for either side in this game, but I don’t trust the pitching on either side and we’ve seen double digit totals in each of the first two games of this series. I think we have another offensive display to close out the set so give me the over here.
