| MATCHUP | Cincinnati Reds | Milwaukee Brewers |
|---|---|---|
| Team Records | 83-78 | 96-65 |
| Where | American Family Field, Milwaukee, Wisconsin | |
| When | Sunday, September 28, 2025 | |
| Time | 03:10 PM EDT | |
| TV | MLB.TV | |
The Cincinnati Reds and the Milwaukee Brewers meet Sunday in MLB action from American Family Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. Milwaukee Brewers prediction.
Starting Pitching Matchup
The Cincinnati Reds will trot out Brady Singer for the start here and Singer is 14-11 with a 3.95 ERA and 158 strikeouts this season. In his career, Singer is 2-1 with a 4.11 ERA and 15 strikeouts against Milwaukee. The Milwaukee Brewers will send out Freddy Peralta here and Peralta is 17-6 with a 2.68 ERA and 201 strikeouts this season. In his last five starts against Cincinnati, Peralta is 1-2 with a 3.20 ERA and 37 strikeouts.
Cincinnati Reds Recap
The Cincinnati Reds come into this game looking to add on to their 7-4 win over the Brewers from Saturday’s matchup to improve to 83-78 this season.
Reds Win And They’re In
Elly De La Cruz has 163 hits with 21 home runs, 5 RBIs, 31 doubles and 36 stolen bases while TJ Friedl has 147 hits with 21 doubles, 13 home runs and 50 RBIs with 12 stolen bases. Gavin Lux has added 117 hits with 26 doubles and 53 RBIs while Spencer Steer has 21 home runs and 74 RBIs and Matt McLain has added 15 homers, 49 RBIs and 18 stolen bases as well on the year. Jose Trevino’s also chipped in 20 doubles as well this season.
Milwaukee Brewers Recap
The Milwaukee Brewers come into this game looking to bounce back from their loss at the hands of Cincinnati on Saturday to drop to 96-65 this season.
Brewers Lose 5 Of Last 6
Brice Turang has 165 hits with 18 home runs, 78 RBIs and 24 stolen bases while Jackson Chourio has 145 hits with a team-high 34 doubles, 19 stolen bases, 20 home runs and 77 RBIs and Sal Frelick has 151 hits as well as 3 triples, 12 home runs, 63 RBIs and 19 stolen bases so far this season. Christian Yelich also has 16 stolen bases with 29 homers and 102 RBIs while also adding 20 doubles. Yelich also has a team-high 162 strikeouts up to this point in the year. William Contreras has 17 homers and 76 RBIs as well this season. Joey Ortiz has chipped in 107 hits with 17 doubles, 7 home runs and 45 RBIs and Caleb Durbin also has 25 doubles with 11 homers and 53 RBIs.
Cincinnati Reds @ Milwaukee Brewers Betting Trends: September 28, 2025
- Probable Starting Pitcher: Freddy Peralta Record this season: 17-6 ERA: 2.68
- Home Record: 9-1
- Last 5 against Reds: 1-2
Why the Milwaukee Brewers will win
- The Brewers have won each of their last 10 day games against NL Central opponents following a home loss.
- The Reds have lost each of their last six day games against the Brewers following a win.
- The Reds have failed to cover the run line each of their last six day games against teams that held a winning record.
- The Brewers have covered the run line in each of their last four day games against the Reds following a loss.
- The Reds have trailed after 3 innings in three of their last four road games.
- The Brewers have led after 5 innings in three of their last four day games against National League opponents that held a winning record.
- Probable Starting Pitcher: Brady Singer Record this season: 14-11 ERA: 3.95
- Road Record: 6-6
- Last 5 against Brewers: 2-1
Why the Cincinnati Reds will win
- The underdogs have won each of the Brewers’ last six games.
- The Brewers have lost seven of their last eight games as favorites against National League opponents.
- The Brewers have failed to cover the run line in each of their last nine games as favorites against National League opponents.
- The Reds have covered the run line in each of their last nine games as underdogs against National League opponents.
- The Reds have led after 3 innings in three of their last four games against opponents that held a winning record.
- The Reds have led after 5 innings in each of their last four day games against NL Central opponents.
Total Runs Facts
- Sixteen of the Reds’ last 18 day games against National League opponents have gone UNDER the total runs line.
- Five of the Brewers’ last six games as favorites against the Reds have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last seven games.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the last eight games between the Reds and Brewers at American Family Field.
Milwaukee Brewers Player Prop Facts
- Jackson Chourio has hit a home run in each of his last two appearances against the Reds after playing the previous day.
- Brice Turang has recorded a Double in four of the Brewers’ last five games as favorites against the Reds.
- Freddy Peralta has recorded six or more strikeouts in each of his last nine appearances.
- Brice Turang has recorded at least one hit in each of the Brewers’ last nine games as favorites against the Reds.
- Freddy Peralta has recorded a win in six of his last seven home appearances against NL Central opponents.
- Freddy Peralta ranks 4th in the league for Wins (17) this season.
Cincinnati Reds Player Prop Facts
- Spencer Steer has hit at least one home run in three of his last six appearances with the Reds as underdogs against NL Central opponents.
- Brady Singer has recorded six or more strikeouts in each of his last six appearances in day games.
- Jose Trevino has recorded a Double in each of his last three road appearances against NL Central opponents that held a winning record.
- Austin Hays has recorded at least one hit in each of his last 10 appearances with the Reds as underdogs.
- Brady Singer has recorded a win in four of his last five appearances in day games.
- Elly De La Cruz ranks 7th in the league in Steals (37) this season.
Matchup/League Facts
- The Brewers rank 2nd in the league for steals this season (162).
- The Brewers rank 2nd in the league for ERA this season (3.59).
- The Reds rank 7th in the league for opponent batting average this season (.233).
- The Reds rank 7th in the league for hits allowed this season (1253).
Cincinnati Reds vs. Milwaukee Brewers Prediction
I’m on the Reds in this game. I just think the Brewers’ focus right now is on the postseason, and while Peralta’s one of their best, I have to wonder how long the Brewers will let him roll out to make sure he stays healthy. The Reds are in do or die, win and you’re in mode and they’ve been finding a way in this series. Give me Cincinnati here.