Cincinnati Reds vs Los Angeles Dodgers Prediction 10/1/2025 Today’s MLB Picks
Chris Ruffolo
Sep 30, 2025; Los Angeles, California, USA; Los Angeles Dodgers designated hitter Shohei Ohtani (17) hits a two run home run during the sixth inning against the Cincinnati Reds during game one of the Wildcard round for the 2025 MLB playoffs at Dodger Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images
Cincinnati (83-79) vs Los Angeles (93-69)
October 1, 2025 at 09:00 PM EDT
The Line: Betting Odds: Los Angeles -250 — Over/Under: +7.5
The Cincinnati Reds and the Los Angeles Dodgers meet Wednesday in MLB NL Wild Card action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Reds vs. Los Angeles Dodgers prediction.
Starting Pitching Matchup
The Cincinnati Reds will send out Zack Littell for the start here and Littell was 10-8 with a 3.81 ERA and 130 strikeouts in the regular season. Yoshinobu Yamamoto will start this one for the Dodgers and was 12-8 with a 2.49 ERA and 201 strikeouts in the regular season.
Cincinnati Reds Recap
The Cincinnati Reds come into this game looking to bounce back from a 10-5 loss at the hands of the Dodgers in Tuesday’s series opener.
Reds Attempting To Find Upset To Force Game Three
Elly De La Cruz has 166 hits with 22 home runs, 86 RBIs, 31 doubles and 37 stolen bases while TJ Friedl has 151 hits with 22 doubles, 14 home runs and 53 RBIs with 12 stolen bases. Gavin Lux has added 120 hits with 28 doubles and 53 RBIs while Spencer Steer has 21 home runs and 75 RBIs and Matt McLain has added 15 homers, 50 RBIs and 18 stolen bases as well on the year. Jose Trevino’s also chipped in 20 doubles as well this season.
Los Angeles Dodgers Recap
The Los Angeles Dodgers come into this game looking to finish the job after a big win to start the playoffs on Tuesday.
Dodgers Looking To Complete Wild Card Sweep
Shohei Ohtani has 172 hits including 25 doubles, 55 home runs, 102 RBIs and 9 triples. Michael Conforto has 83 hits with 20 doubles while Teoscar Hernandez has 126 hits with 25 home runs, 29 doubles and 89 RBIs as well this season. Ohtani has a team-high 20 stolen bases while Max Muncy has 10 doubles but also has 83 strikeouts so far this season. Mookie Betts has also chipped in 20 home runs and 82 RBIs as well on the year. Freddie Freeman has also logged 164 hits with a team-high 39 doubles, 24 home runs and 90 RBIs. Andy Pages also has 158 hits with 27 doubles, 27 home runs and 86 RBIs as well this season.
Cincinnati Reds vs. Los Angeles Dodgers Prediction
I’m rolling with the Dodgers here. I said when the Reds picked up Zack Littell that the move made no sense to me, putting a home-run prone starter at Great American Ballpark, but even on the road I can’t see him doing well against a Dodger lineup that was cranking in game one. The Reds made it interesting late, but it still wasn’t enough and I don’t think it will be here either. Give me the Dodgers.