Cincinnati Reds vs Baltimore Orioles Prediction 4/19/25 MLB Picks

The Cincinnati Reds and Baltimore Orioles meet Saturday in MLB action at Oriole Park at Camden Yards. Here’s a Cincinnati Reds vs Baltimore Orioles Prediction. This article will include a Cincinnati Reds vs Baltimore Orioles Pick.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 10-10 on the year and play the Marlins, Rockies, and Cardinals next. The Cincinnati Reds are batting .218 on the season, have a .296 OBP, and a .351 slugging percentage. The Cincinnati Reds pitching staff has a 3.08 ERA and a 1.01 WHIP. TJ Friedl leads the Cincinnati Reds with 19 hits and 7 RBI, while Elly De La Cruz and Gavin Lux have combined for 37 hits and 28 RBI. 

Hunter Greene gets the ball for the Cincinnati Reds, and he is 2-1 with a 0.98 ERA and 31 strikeouts this season. This will be Greene’s second career game against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 8-11 on the year and play the Nationals, Tigers, and Yankees next. The Baltimore Orioles are batting .229 on the season, have a .296 OBP, and a .399 slugging percentage. The Baltimore Orioles pitching staff has a 4.45 ERA and a 1.43 WHIP. Cedric Mullins leads the Baltimore Orioles with 17 hits and 18 RBI while Ryan O’Hearn and Ryan Mountcastle have combined for 30 hits and 10 RBI.

Brandon Young will make his major league debut when he takes the mound. Young was 11-15 with a 3.57 ERA and 313 strikeouts in his minor league career. Young was 6-5 with a 3.65 ERA and 109 strikeouts in his two-year college career at Louisiana-Lafayette.

Why the Baltimore Orioles will win

• The Orioles have won six of their last seven games as underdogs following a loss.
• The Reds have lost 11 of their last 13 games as favorites against American League opponents.
• The Reds have failed to cover the run line in each of their last six day games following a road win.
• The Orioles have covered the run line in each of their last four games as underdogs against the Reds.
• The Orioles have led after 3 innings in six of their last eight games against the Reds at Oriole Park at Camden Yards.

Why the Cincinnati Reds will win

• The Orioles have lost eight of their last nine home games against NL Central opponents.
• The Reds have won four of their last five games against teams that held a losing record.
• The Orioles have failed to cover the run line in each of their last eight Saturday home games.
• The road team has covered the run line in seven of the last eight games between the Reds and Orioles.
• The Orioles have trailed after 5 innings in each of their last four games as home underdogs.
• The Reds have led after 3 innings in each of their last six Saturday games against opponents that held a losing record.

Cincinnati Reds vs Baltimore Orioles Prediction

The Orioles continue to underachieve and this isn’t a spot I want to back them. I have a thing where I usually avoid pitchers making their big league debut as we don’t have a sample size to use. We don’t know how Young is going to perform for the first time. Young is also outside of the top-15 prospects for the Orioles due to his inability to miss bats or have an elite pitch. The Reds have caught fire offensively lately and they’ve rebounded nicely after losing six of their first eight games. Also, Greene is finally coming into his own and has the best ERA in baseball right now. Greene is looking more and more like an ace. You could argue this price should be much steeper. I’ll gladly lay the cheap price with the Reds on Saturday. 

Randy Chambers's Pick: Cincinnati Reds -125