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Chicago White Sox vs Tampa Bay Rays Prediction 07/23/2025 Picks

Jul 5, 2025; Minneapolis, Minnesota, USA; Tampa Bay Rays starting pitcher Taj Bradley (45) throws to the Minnesota Twins in the first inning at Target Field. Mandatory Credit: Bruce Kluckhohn-Imagn Images

Jul 5, 2025; Minneapolis, Minnesota, USA; Tampa Bay Rays starting pitcher Taj Bradley (45) throws to the Minnesota Twins in the first inning at Target Field. Mandatory Credit: Bruce Kluckhohn-Imagn Images

Chicago (36-66) vs Tampa Bay (53-49)

July 23, 2025 at 07:35 PM EDT

The Line: Betting Odds: Tampa Bay -1.5 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate a White Sox vs Rays prediction for this MLB game on Wednesday, July 23, at George M. Steinbrenner Field in Tampa, Florida. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Betting Preview

The Chicago White Sox (36-66, 15-36 Away) started the second half of the season with their first sweep of the year by defeating the Pirates in three games on the road. The White Sox made it four in a row after winning Game 1 of the series against the Rays, but fell short 4-3 in Game 2 last night. Davis Martin took the loss after allowing four runs (three earned) on three hits with three strikeouts and four walks in 5.0 innings.

This season, the White Sox average 3.63 runs per game (27th in the MLB) on a .224/.298/.353 triple-slash. When it comes to pitching, the White Sox’s staff has a 4.04 ERA (19th) and 1.37 WHIP (25th). Miguel Vargas leads the White Sox with a .221 batting average, 12 home runs, and 40 RBI this season.

Jonathan Cannon will take the mound for the White Sox on Wednesday. The 25-year-old right-hander has a 4-7 record in 14 starts this year with a 4.18 ERA and 1.38 WHIP in 84.0 innings.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays (53-49, 31-27 Home) were swept by the Red Sox in the last series of the first half, but responded with a series win over the Orioles. Following a loss to the White Sox in Game 1 of the current series, the Rays edged them out 4-3 on Tuesday. Jose Caballero led the offense with two RBI, while Drew Rasmussen pitched for 4.0 innings in a no-decision, allowing two runs on three hits with five strikeouts and one walk. Edwin Uceta was credited with the win.

This year, the Rays average 4.65 runs per game (9th in the MLB) on a .257/.320/.405 triple-slash. When it comes to pitching, the Rays’ staff has a 3.80 ERA (11th) and 1.20 WHIP (3rd). Junior Caminero leads the Rays with a .260 batting average, 25 home runs, and 65 RBI this season.

The projected starting pitcher for the Rays is Taj Bradley, who is 6-6 in 20 starts this season, with a 4.35 ERA and 1.24 WHIP in 109.2 innings.

Total Runs Facts

Ten of the White Sox’s last 12 games against AL East opponents have gone UNDER the total runs line.
Four of the Rays’ last five home games against AL Central opponents have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last eight night games between the White Sox and Rays.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the White Sox’s last six games against AL East opponents.

Matchup/League Facts

The Rays are one of only four teams in the league to rank top 10 in both steals and batting average this season.
The Rays rank 4th in the league for walks allowed this season (282).
The White Sox rank 29th in the league for slugging percentage this season (.353).
The White Sox rank 29th in the league for on-base percentage this season (.297).

White Sox vs Rays Prediction

The White Sox won six of the previous ten H2H encounters, but the Rays were better in three of the last four. Although I am leaning toward the Rays in this one, I will opt for Under instead. Both Jonathan Cannon and Taj Bradley have improved recently, and both could register quality starts here. Cannon allowed five runs in three starts in July, while Bradley surrendered nine runs in his previous five starts, recording a couple of shutouts in the process. These two are not the best pitchers in their respective rotations, but I am backing them to continue with fine form. Go with Under.

Oliver Zivic's Pick: Under 9.5

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