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Chicago White Sox vs New York Mets Prediction 5/26/25 MLB Picks

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New York Mets (32-21) vs Chicago White Sox (17-36)

Game Info: Monday, May 26, 2025 at 4:10 pm (Citi Field)

The Line: Betting Odds: New York Mets -310 / Chicago White Sox +250 — Over/Under: 8.5

(Get latest betting odds)

The Chicago White Sox and the New York Mets meet Monday in MLB action from Citi Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs. New York Mets prediction.

Starting Pitching Matchup

The Chicago White Sox will send out Adrian Houser for the start here, and Houser is 1-0 with a 0.00 ERA and 2 strikeouts this season. In his career, Houser is 1-1 with a 3.52 ERA and 8 strikeouts against the Mets. Clay Holmes will start this one for the Mets and is 5-3 with a 3.13 ERA and 53 strikeouts this season. This will be Holmes’ first career start against the White Sox.

Chicago White Sox Recap

The Chicago White Sox come into this game looking to bounce back from a 5-4 loss at the hands of the Texas Rangers last time out to fall to 17-36 on the year. After this series, the White Sox will head on the road for a series against the Baltimore Orioles.

White Sox Pick Up Rare Series Win

Lenyn Sosa leads the White Sox with 49 hits, including 9 doubles and 16 RBIs. Andrew Benintendi has 21 hits, including 5 home runs, 15 RBIs, and a .219 batting average, while Miguel Vargas has a team-high 12 doubles, 7 home runs, and 23 RBIs. Brooks Baldwin has also added 16 RBIs, while Luis Robert Jr. has a team-high 20 stolen bases along with 20 RBIs so far this season. Andrew Vaughn has 5 home runs and 19 RBIs as well as 8 doubles this season.

Why the Chicago White Sox will win

Chicago White Sox Player Prop Facts

New York Mets Recap

The New York Mets come into this game looking to add on to their 3-1 win over the Los Angeles Dodgers from Sunday’s series finale to improve their record to 32-21 on the year. After this series, the Mets will welcome the Colorado Rockies to town.

Mets Pick Up Big Series Win Vs. Dodgers

Pete Alonso has 57 hits with 16 doubles, 10 home runs, 40 RBIs, and a .291 batting average, while Juan Soto has 45 hits with 10 doubles, 8 home runs, and 24 RBIs on the year. Francisco Lindor has 57 hits with 9 stolen bases along with 9 doubles, 10 home runs, and 29 RBIs, while Mark Vientos has 5 home runs, 18 RBIs, but 41 strikeouts so far this season. Brandon Nimmo has also added 38 hits with 9 doubles and 8 home runs, and 27 RBIs this season. Luis Torrens has also chipped in 9 doubles, and Luisangel Acuna has 11 stolen bases as well this season.

Why the New York Mets will win

New York Mets Player Prop Facts

Total Runs Facts

Chicago White Sox vs. New York Mets Prediction

I’m on the Mets here. I know the White Sox had a solid series this past weekend against Texas, but the Mets looked really good in their own right against a tougher opponent in the Dodgers, and I’m not sold on Adrian Houser after one start back. The Mets know what he’s tossing, and I think that the White Sox will have trouble matching against Clay Holmes here. Give me the Mets in this one.

Chris Ruffolo's Pick: New York Mets -310

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