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Chicago White Sox vs Milwaukee Brewers Prediction 3/28/2026 Today’s MLB Picks

Oct 13, 2025; Milwaukee, Wisconsin, USA: Milwaukee Brewers relief pitcher Chad Patrick (39) reacts after giving up a home run to Los Angeles Dodgers first baseman Freddie Freeman (5) during the sixth inning during game one of the NLCS round for the 2025 MLB playoffs at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images

Oct 13, 2025; Milwaukee, Wisconsin, USA: Milwaukee Brewers relief pitcher Chad Patrick (39) reacts after giving up a home run to Los Angeles Dodgers first baseman Freddie Freeman (5) during the sixth inning during game one of the NLCS round for the 2025 MLB playoffs at American Family Field. Mandatory Credit: Benny Sieu-Imagn Images

MATCHUP Chicago White Sox Milwaukee Brewers
Team Records 0-1 1-0
Spread +1.5 -131 -1.5 109
Moneyline +159 -194
Total Over 8.5 (-102) Under 8.5 (-118)
Where American Family Field, Milwaukee, Wisconsin
When Saturday, March 28, 2026
Time 07:10 PM EDT
TV MLB.TV
In this article, we will formulate a White Sox vs Brewers Prediction for this MLB matchup on Saturday, March 28th. Let’s take a look at the prediction for this MLB matchup.

Milwaukee Brewers Preview


The Milwaukee Brewers have a 1-0 record this season and are sitting on the first place of the NL Central. They are coming off a 14-2 home win over the White Sox and their previous three games were a 4-1 home win over the Reds, a 9-1 home win over the Reds, and a 12-0 road loss to the Cubs in spring training.

The Brewers have a .364 batting average this season, .512 OBP and .606 Slugging percentage. Milwaukee’s pitching staff has a 2.00 ERA and 1.00 WHIP. Christian Yelich is the team’s best hitter with a .500 batting average. Jake Bauers leads the team in RBI with 3, also adding a team-high one home run.

Chad Patrick (R) is the projected starting pitcher for the Brewers, and last season he had a 3-8 record, 3.53 ERA and 1.28 WHIP.

Chicago White Sox Preview


The Chicago White Sox have a 0-1 record this season and are sitting on the last place of the AL Central. They are coming off a 14-2 road defeat by the Brewers and their previous three games were a 10-9 road loss to the Athletics, a 4-2 road loss to the Mariners, and an 11-7 road loss to the Reds in spring training.

The White Sox have a .129 batting average this season, .250 OBP and .323 Slugging percentage. Chicago’s pitching staff has a 14.63 ERA and 2.75 WHIP. Munetaka Murakami is the team’s best hitter with a .500 batting average, also adding a team-high one home run and leading the team in RBI with one.

Sean Burke (R) is the projected starting pitcher for the White Sox, and last season he had a 4-11 record, 4.29 ERA and 1.45 WHIP.

The Chicago White Sox @ Milwaukee Brewers Betting Trends: March 28, 2026


Why the Milwaukee Brewers will win


Why the Chicago White Sox will win

Total Runs Facts

Milwaukee Brewers Player Prop Facts

Chicago White Sox Player Prop Facts

Matchup/League Facts

White Sox vs Brewers Prediction


The Brewers are 9-1 in their last 10 meetings against the White Sox, having won their last four meetings in Milwaukee. Over is 6-1-1 in their last 8 meetings.

In this White Sox vs Brewers Prediction, the Brewers are coming as -200 home favorites. The Brewers destroyed the White Sox in opening day and I don’t expect a different outcome today. The Brewers have been dominating the White Sox in recent years and their last four home victories have been by a combined 36-13 score. I don’t trust Burke for Chicago, even though he had a shutout start against Milwaukee last season and Chicago’s bullpen looked atrocious in the opening day, with 11 earned runs. Take the Brewers on the runline for another comfortable win today.

Nikos Lagouretos's Pick: Milwaukee Brewers -1.5

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