Chicago White Sox vs Cleveland Guardians Prediction 4/10/25 MLB Picks

David Racey

1 year ago

Cleveland Guardians (5-6) vs Chicago White Sox (2-9)

Game Info: Thursday, April 10, 2025 at 1:10 pm (Progressive Field)

The Line: Betting Odds: Cleveland Guardians -238 / Chicago White Sox +195 — Over/Under: 7.5

In this article, we will formulate a Chicago White Sox vs Cleveland Guardians prediction for this MLB game on Thursday, April 10th, at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Betting Preview

The Chicago White Sox are 2-9 this year after they lost the first two games in this series by scores of 1-0 and 3-2. In the game two loss, the White Sox led 1-0 in the first, but they allowed the next three runs before scoring once in the ninth and getting thrown at home to end the game. Chicago recorded eight hits in the game, and they were led by Vargas and Sosa, who both had one RBI in the loss. The White Sox started Burke, who allowed three hits and three earned runs over 3.0 innings, while Vasil, Murfee, and Ellard combined for five shutout innings out of the bullpen.

Prior to this series, the White Sox were swept by the Tigers in three games and lost two out of three against the Twins. The Chicago pitching staff has a 3.72 ERA with a 1.26 WHIP and a .209 opponent batting average, while their offense has scored 34 runs with a .202 batting average and a .276 on-base percentage this season. Andrew Benintendi has led Chicago with two home runs and six RBIs, but he is now on the IL, while Brooks Baldwin has added one home run and five RBIs this year. The projected starting pitcher for Chicago is Jonathan Cannon, who is 0-1 with a 3.12 ERA and a 1.50 WHIP over 8.2 innings pitched this year.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 5-6 this season after they won game two in this series by a score of 3-2 on Wednesday. Cleveland fell behind early, but they scored three runs in the first three innings of the game and were able to barely escape with the win. The Guardians recorded just three hits, and they committed one error, while they were led by Santana and Noel, who both had one RBI in the win. Cleveland started Allen, who allowed just four hits over 4.2 innings, while Clase allowed one earned run in the ninth but still got the save.

Prior to this series, the Guardians lost two out of three against the Angels and were swept by the Padres in three games before that. The Cleveland pitching staff has a 4.21 ERA with a 1.47 WHIP and a .264 opponent batting average, while their offense has scored 38 runs with a .204 batting average and a .300 on-base percentage this season. Kyle Manzardo has led Cleveland with three home runs and nine RBIs, while Jose Ramirez has added four home runs and six RBIs this year. The projected starting pitcher for Cleveland is Gavin Williams, who is 0-0 with a 4.50 ERA and a 1.63 WHIP over 8.0 innings pitched this season.

Why the Guardians will beat the White Sox

The White Sox have lost each of their last seven games against American League opponents.
The Guardians have won each of their last six home games against teams that held a losing record.
The Guardians have covered the run line in 10 of their last 11 day games against American League opponents following a win.
The White Sox have failed to cover the run line each of their last six Thursday games against AL Central opponents that held a losing record.
The White Sox have trailed after 3 innings in four of their last five games against American League opponents that held a losing record.
The White Sox have trailed after 5 innings in four of their last five games against AL Central opponents that held a losing record.

Why the White Sox will beat the Guardians

The Guardians have lost four of their last five games as favorites against the White Sox following a home win.
The Guardians have failed to cover the run line in each of their last seven home games against the White Sox following a home win.
The White Sox have covered the run line in seven of their last eight games against American League opponents following a road loss.

Total Runs Facts

Five of the Guardians’ last six home games after playing the previous day have gone UNDER the total runs line.
Each of the White Sox’s last three games against AL Central opponents have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the White Sox’s last seven day games.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Guardians’ last seven day games.

Cleveland Guardians Player Prop Facts

Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites.
Steven Kwan has recorded at least one Single in 12 of his last 14 appearances after playing the previous day.
Carlos Santana has recorded at least one hit in each of his last eight appearances with his team as a home favorite against AL opponents.
Steven Kwan has scored at least one run in each of his last four appearances against the White Sox after playing the previous day.
Carlos Santana has hit a home run in four of his last seven appearances with the Guardians as home favorites against the White Sox.
Lane Thomas has recorded at least one RBI in five of his six previous appearances with his team as a favorite against the White Sox.

Chicago White Sox Player Prop Facts

Andrew Benintendi has hit at least one home run in three of his last seven road appearances against opponents that held a losing record.
Andrew Benintendi has recorded at least one Single in eight of his last nine appearances against AL opponents that held a losing record.
Andrew Benintendi has recorded at least one hit in each of his last nine appearances against AL opponents that held a losing record.
Korey Lee has scored a run in three of his last four road appearances against AL opponents that held a losing record.