Cleveland (44-49) vs Chicago (32-63)
July 12, 2025 at 04:10 PM EDT
The Line: Betting Odds: Chicago +135 — Over/Under: +8.5
The Cleveland Guardians and the Chicago White Sox meet Saturday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cleveland Guardians vs. Chicago White Sox prediction.
Starting Pitching Matchup
Tanner Bibee will get the start for the Guardians here and Bibee is 4-9 with a 4.35 ERA and 90 strikeouts this season. In his career, Bibee is 1-0 with a 6.55 ERA and 8 strikeouts against the White Sox. Sean Burke will get the nod for the White Sox here and Burke is 4-8 with a 4.40 ERA and 75 strikeouts this season. This will be Burke’s second career start against the Guardians.
Cleveland Guardians Recap
The Cleveland Guardians come into this game looking to rebound after being forced to settle for a double-header split with the White Sox on Friday, winning game one by a final score of 4-2 before falling short in game two by a score of 5-4, sitting at 44-49 on the year. After this series, the Guardians will head home to take on the Athletics.
Guardians Four-Game Win Streak Is No More
Steven Kwan has 101 hits as part of a .292 batting average and 6 home runs, 20 doubles and 29 RBIs. Kyle Manzardo has 55 hits with 11 doubles, 2 triples, 13 home runs and 33 RBIs as well this year. Gabriel Arias has 17 doubles but also 88 strikeouts and Manzardo has 73 strikeouts so far this season. Arias has also added 6 home runs and 31 RBIs and Jose Ramirez has chipped in 17 home runs and 45 RBIs. Carlos Santana has also added 69 hits with 10 home runs and 38 RBIs as well this season.
Why the Cleveland Guardians will win
The White Sox have lost each of their last eight day games against teams that held a losing record.
The Guardians have won 12 of their last 13 day games against the White Sox following a road loss.
The White Sox have failed to cover the run line in 16 of their last 17 day games against the Guardians at Rate Field following a win.
The Guardians have covered the run line in each of their last seven road games after playing the previous day.
Cleveland Guardians Player Prop Facts
Jose Ramirez has hit a home run in four of the Guardians’ last five games against AL opponents.
Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites against AL opponents.
Lane Thomas has recorded at least one hit in each of his 12 previous road appearances against AL Central opponents that held a losing record.
Jose Ramirez ranks T4th in the league in Steals (26) this season.
Chicago White Sox Recap
The Chicago White Sox come into this game looking to build on their double-header split with the Guardians to improve to 32-63 this season. After this series, the White Sox will take on the Pittsburgh Pirates on the road following the all-star break.
White Sox Alternate Wins & Losses In Four Straight
Lenyn Sosa has 74 hits including 14 doubles and 29 RBIs. Andrew Benintendi has 51 hits including 10 doubles, 10 home runs, 34 RBIs and a .223 batting average while Miguel Vargas has 72 hits, 21 doubles, 10 home runs and 34 RBIs. Brooks Baldwin has also added 20 RBIs while Luis Robert Jr. has a team-high 22 stolen bases along with 32 RBIs so far this season. Chase Meidroth has added 61 hits with 11 stolen bases as well as 6 doubles this season.
Why the Chicago White Sox will win
The White Sox have won four of their last five games as home underdogs after going to extra innings.
The Guardians have lost four of their last five games as favorites after going to extra innings.
The White Sox have covered the run line in each of their last nine games against American League opponents after going to extra innings.
The Guardians have failed to cover the run line in 11 of their last 12 games as favorites after going to extra innings.
Chicago White Sox Player Prop Facts
Luis Robert has hit a home run in three of his last 10 appearances with the White Sox as home underdogs against the Guardians.
Luis Robert has recorded at least one hit in 14 of his last 16 appearances against the Guardians.
Michael A. Taylor has recorded a Double in three of his last four appearances after playing the previous day.
Luis Robert ranks T10th in the league in Steals (22) this season.
Total Runs Facts
Seven of the White Sox’s last eight day games after playing the previous day have gone UNDER the total runs line.
Six of the Guardians’ last seven games after going to extra innings have gone UNDER the total runs line.
Cleveland Guardians vs. Chicago White Sox Prediction
I’m on the Guardians here. I get the case to be made for the White Sox, but I just can’t trust them in a spot like this with Cleveland’s staff ace on the mound in Tanner Bibee. Bibee is a better arm than what he’s shown in a lot of his starts to this point and I think that the Guardians rally behind him to get another key win going into the break. Give me Cleveland.