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Chicago White Sox vs Cincinnati Reds Prediction 5/13/25 MLB Picks

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Cincinnati Reds (20-22) vs Chicago White Sox (12-29)

Game Info: Tuesday, May 13, 2025 at 6:40 pm (Great American Ball Park)

The Line: Betting Odds: Cincinnati Reds -198 / Chicago White Sox +164 — Over/Under: 9.5

(Get latest betting odds)

The Chicago White Sox and Cincinnati Reds meet Tuesday in MLB action at Great American Ball Park. Here’s a Chicago White Sox vs Cincinnati Reds Prediction. This article will include a Chicago White Sox vs Cincinnati Reds Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 12-29 on the year and play the Cubs, Mariners, and Rangers next. The Chicago White Sox are batting .214 on the season, have a .291 OBP, and a .321 slugging percentage. The Chicago White Sox pitching staff has a 4.10 ERA and a 1.39 WHIP. Lenyn Sosa leads the Chicago White Sox with 36 hits and 10 RBI, while Miguel Vargas and Andrew Vaughn have combined for 58 hits and 29 RBI. 

Jonathan Cannon gets the ball for the Chicago White Sox, and he is 2-4 with a 4.09 ERA and 33 strikeouts this season. This will be Cannon’s first career game against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 20-22 on the year and play the Guardians, Pirates, and Cubs next. The Cincinnati Reds are batting .237 on the season, have a .321 OBP, and a .377 slugging percentage. The Cincinnati Reds pitching staff has a 3.75 ERA and a 1.19 WHIP. TJ Friedl leads the Cincinnati Reds with 43 hits and 17 RBI, while Elly De La Cruz and Gavin Lux have combined for 77 hits and 47 RBI.

Andrew Abbott gets the ball for the Cincinnati Reds, and he is 2-0 with a 2.25 ERA and 31 strikeouts this season. This will be Abbott’s second career game against the Chicago White Sox.

Why the Cincinnati Reds will win

Why the Chicago White Sox will win

Cincinnati Reds Player Prop Facts

Chicago White Sox Player Prop Facts

Chicago White Sox vs Cincinnati Reds Prediction

As I’ve said all year, the White Sox are a team we’ve faded endlessly these last three years, and it’s not going to stop now. The White Sox have won two straight games just twice this season. In 28.2 road innings, Cannon has a 5.65 ERA and a .267 allowed batting average. No, thanks. The Reds need to take advantage of games like this if they’re going to right the ship. Abbott has allowed seven hits and zero runs in his last nine innings. Abbott has allowed one or fewer runs in four of his first five starts. In nine home innings, Abbott has a 1.00 ERA and .161 allowed batting average. There’s no excuse for the Reds in a series like this. Of course, give me the RL to shave down the juice. 

Randy Chambers's Pick: Cincinnati Reds -1.5

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