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Chicago Cubs vs Washington Nationals Prediction 6/5/25 MLB Picks

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Washington Nationals (29-32) vs Chicago Cubs (38-23)

Game Info: Thursday, June 5, 2025 at 6:45 pm (Nationals Park)

The Line: Betting Odds: Washington Nationals +120 / Chicago Cubs -142 — Over/Under: 9.5

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The Chicago Cubs are visiting the Washington Nationals on Thursday, June 5th at the Nationals Park in the third game of this series, with both teams being tied 1-1 wins. We will look at this from a betting perspective and determine the best bets for this game. Here’s the Chicago Cubs vs Washington Nationals Prediction. We will examine:

The Washington Nationals’ recent form and player performance

The Chicago Cubs’ recent form and player performance

Recent betting trends and streaks involving the Washington Nationals

Recent betting trends and streaks involving the Chicago Cubs

Recent betting trends in games played between the Chicago Cubs vs Washington Nationals

A summary that ties it all together and produces a favorable betting outcome for the Chicago Cubs vs Athletics game

Washington Nationals Preview

The Washington Nationals have a 29-32 record this season and are sitting in third place in the NL East. The Nationals have a 14-15 home record and are 30-29 in over/under. They are coming off a 2-0 home victory over the Cubs, which ended their previous two-game losing streak. Over is 6-2 in their last 8 games, and they are playing the Mets and the Rangers next.

The Nationals have a .243 batting average this season, a .311 OBP, and a .394 Slugging percentage. Washington’s pitching staff has a 4.99 ERA and 1.38 WHIP. James Wood leads the Nationals with 65 hits, 45 RBI and a team-high 16 home runs, while being the team’s best hitter with a .283 batting average.

Jake Irvin (R) will take the mound for the Nationals, and he has a 5-1 record, 3.93 ERA, and 1.17 WHIP. He has been better at home with a 3.19 ERA across six home starts, but he is coming off his worst start of the season, where he gave up 6 runs across 5 innings of work against the Diamondbacks. Jake Irvin is 0-2 with an ERA of 9.00 and 12 strikeouts in 3 appearances against the Cubs in his career.

Chicago Cubs Preview

The Chicago Cubs have a 38-23 record this season and are sitting in first place in the NL Central. The Cubs have an 18-12 road record and are 33-22 in over/under. They are coming off a 0-2 road defeat by the Nationals, which ended their three-game winning streak. Under is 5-2-1 in their last 8 games, and they are playing the Tigers and the Phillies next.

The Cubs have a .260 batting average this season, a .334 OBP, and a .443 Slugging percentage. Chicago’s pitching staff has a 3.80 ERA and 1.24 WHIP. Nico Hoerner leads the Cubs with 66 hits, and he is the team’s best hitter with a .296 batting average. Seiya Suzuki leads the team in RBI, with 53.

Drew Pomeranz (R) will take the mound for the Cubs, and he has been a reliever, which means that Chicago will go for a bullpen game today. Pomeranz has a 2-0 record, 0.00 ERA, and 0.51 WHIP. Drew Pomeranz has a 2-1 record with an ERA of 3.15 and 24 strikeouts in 6 appearances versus the Nationals in his career.

Why the Washington Nationals will win

Why the Chicago Cubs will win

Total Runs Facts

Matchup/League Facts

Chicago Cubs vs Washington Nationals Prediction

The Cubs are 7-2 in their last 9 overall meetings against the Nationals, and are 5-1 in their last 6 visits in Washington. Under is 4-1 in their last 5 meetings.

In this Chicago Cubs vs Washington Nationals Prediction, the Cubs are coming as -150 road favorites. The Cubs are rightfully favored, as they have a better overall record this season and have been very good on the road, while the Nationals have been average at home. The Nationals have the second-worst bullpen in the league, while the Cubs are second in the MLB in runs scored. The Nationals are weaker against lefties, and Irvin has an expected ERA of 5.09; and he has been hit hard by Cubs bats in his career. I expect the Chicago Cubs to take care of business on the road in this one.  

Nikos Lagouretos's Pick: Chicago Cubs ML

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