| MATCHUP | Chicago Cubs | St. Louis Cardinals |
|---|---|---|
| Team Records | 31-26 | 29-25 |
| Spread | -1.5 129 | +1.5 -156 |
| Moneyline | -132 | +110 |
| Total | Over 7.5 (-116) | Under 7.5 (-104) |
| Where | Busch Stadium, St. Louis, Missouri | |
| When | Friday, May 29, 2026 | |
| Time | 07:15 PM EDT | |
| TV | MLB.TV | |
The Chicago Cubs and St. Louis Cardinals meet Friday in MLB action at Busch Stadium. Here’s a Chicago Cubs vs St. Louis Cardinals Prediction. This article will include a Chicago Cubs vs St. Louis Cardinals Pick.
Chicago Cubs Betting Preview
The Chicago Cubs are 31-26 on the year and play the Athletics and Giants next. The Chicago Cubs are batting .238 on the season and have a .336 OBP and a .387 slugging percentage. The Chicago Cubs’ pitching staff has a 4.19 ERA and a 1.24 WHIP. Alex Bregman leads the Chicago Cubs with 59 hits and 17 RBI, while Pete Crow-Armstrong and Nico Hoerner have combined for 103 hits and 56 RBI.
Shota Imanaga gets the ball for the Chicago Cubs, and he is 4-5 with a 4.04 ERA and 67 strikeouts this season. Imanaga is 2-1 with a 2.84 ERA and 25 strikeouts in his career against the St. Louis Cardinals.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals are 29-25 on the year and play the Reds and Rangers next. The St. Louis Cardinals are batting .238 on the season, with a .318 OBP and a .383 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.22 ERA and a 1.37 WHIP. Jordan Walker leads the St. Louis Cardinals with 61 hits and 42 RBI, while Alec Burleson and Ivan Herrera have combined for 111 hits and 61 RBI.
Kyle Leahy gets the ball for the St. Louis Cardinals, and he is 5-3 with a 4.44 ERA and 42 strikeouts this season. Leahy is 0-0 with a 3.55 ERA and 4 strikeouts in his career against the Chicago Cubs.
Why the St. Louis Cardinals will win
- The Cubs have lost each of their last six games as favorites after playing the previous day.
- The Cardinals have won five of their last six games as home underdogs against NL Central opponents following a loss.
- The Cubs have failed to cover the run line in each of their last six games as favorites after playing the previous day.
- The Cardinals have covered the run line in eight of their last nine night games following a loss.
Why the Chicago Cubs will win
- The Cubs have won each of their last nine night games against National League opponents following a win.
- The Cardinals have lost eight of their last nine games against NL Central opponents following a road loss.
- The Cubs have covered the run line in each of their last five night games against National League opponents following a road win.
- The Cardinals have failed to cover the run line in each of their last three night games against National League opponents.
- The Cubs have led after 5 innings in each of their last three games against the Cardinals.
Total Runs Facts
- Each of the Cardinals’ last four games as underdogs has gone UNDER the total runs line.
- Six of the Cubs’ last seven road games after playing the previous day have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cardinals’ last six night games.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of Shota Imanaga’s last five appearances as a starter.
St. Louis Cardinals Player Prop Facts
- Alec Burleson has recorded at least one hit in each of the Cardinals’ last seven home games.
- Lars Nootbaar has hit a home run in two of his last three appearances against the Cubs at Busch Stadium.
Chicago Cubs Player Prop Facts
- Alex Bregman has recorded at least one hit in each of his last 13 road appearances after playing the previous day.
- Shota Imanaga has recorded six or more strikeouts in each of his last three road appearances against NL opponents.
- Seiya Suzuki has hit a home run in each of the Cubs’ last three games as favorites against the Cardinals.
Matchup/League Facts
- The Cardinals rank T25th in the league for triples this season (4).
- The Cardinals rank 25th in the league for opponent batting average this season (.254).
- The Cubs rank 2nd in the league for on-base percentage this season (.336).
- The Cubs rank 6th in the league for runs scored this season (272).
Chicago Cubs vs St. Louis Cardinals Prediction
The Cubs stopped the bleeding with two wins over the Pirates, and now they run into an ice-cold Cardinals side. We know what Imanaga is capable of when he’s right, and despite back-to-back brutal starts, he still has a 3.09 ERA and a .202 allowed batting average in 23.1 road innings. In 52 at bats agaisnt current Cardinals, Imanaga is allowing a .192 abtting average and .192 batting average. I’m going to roll with the Cubs and the low price on Friday night.