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Chicago Cubs vs San Francisco Giants Prediction 6/12/2026 Today’s MLB Picks

Jun 11, 2026; Denver, Colorado, USA; MLB second base umpire Chris Guccione (68) listens to Chicago Cubs manager Craig Counsell (11) in the sixth inning against the Colorado Rockiesat Coors Field. Mandatory Credit: Ron Chenoy-Imagn Images

Jun 11, 2026; Denver, Colorado, USA; MLB second base umpire Chris Guccione (68) listens to Chicago Cubs manager Craig Counsell (11) in the sixth inning against the Colorado Rockiesat Coors Field. Mandatory Credit: Ron Chenoy-Imagn Images

MATCHUP Chicago Cubs San Francisco Giants
Team Records 35-34 28-41
Where Oracle Park, San Francisco, California
When Friday, June 12, 2026
Time 10:15 PM EDT
TV MLB.TV
The Chicago Cubs and San Francisco Giants do battle Friday night in an MLB contest at Oracle Park. Here’s a Chicago Cubs vs San Francisco Giants Prediction. This article will include a Chicago Cubs vs San Francisco Giants Pick.

Chicago Cubs Betting Preview


The Chicago Cubs are 35-34 on the year and play the Rockies and Blue Jays next. The Chicago Cubs are batting .239 on the season and have a .332 OBP and a .390 slugging percentage. The Chicago Cubs’ pitching staff has a 4.31 ERA and a 1.25 WHIP. Nico Hoerner leads the Chicago Cubs with 67 hits and 33 RBI, while Pete Crow-Armstrong and Alex Bregman have combined for 133 hits and 54 RBI.

Javier Assad gets the ball for the Chicago Cubs, and he is 3-1 with a 4.73 ERA and 19 strikeouts this season. Assad is 0-0 with a 2.70 ERA and 13 strikeouts in his career against the San Francisco Giants.

San Francisco Giants Betting Preview


The San Francisco Giants are 28-41 on the year and play the Braves and Marlins next. The San Francisco Giants are batting. 259 on the season, have a .309 OBP, and have a .419 slugging percentage. The San Francisco Giants’ pitching staff has a 4.55 ERA and a 1.41 WHIP. Luis Arraez leads the San Francisco Giants with 86 hits and 25 RBI, while Casey Schmitt and Jung Hoo Lee have combined for 147 hits and 62 RBI.

Landen Roupp gets the ball for the San Francisco Giants, and he is 5-6 with a 4.00 ERA and 77 strikeouts this season. Roupp is 0-1 with a 2.53 ERA and 9 strikeouts in his career against the Chicago Cubs.

Why the San Francisco Giants will win

Why the Chicago Cubs will win

Total Runs Facts

San Francisco Giants Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Chicago Cubs vs San Francisco Giants Prediction


Assad has a 4.73 ERA and 1.08 WHIP, and through 18 road innings, he has an 8.00 ERA and a .315 batting average allowed. Roupp has a 4.00 ERA and 1.29 WHIP on the season, and he’s allowed 11 hits and 9 runs in his last 9.2 innings. We have two struggling pitchers and at least one lineup that has explosive potential. In a big park, I expect some runs. I’m going to side with the over in what should be a high-scoring game Friday night.

Randy Chambers's Pick: Over

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