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Chicago Cubs vs Milwaukee Brewers Prediction 10/4/2025 Today’s MLB Picks

Aug 5, 2025; Atlanta, Georgia, USA; Milwaukee Brewers starting pitcher Freddy Peralta (51) throws against the Atlanta Braves in the third inning at Truist Park. Mandatory Credit: Brett Davis-Imagn Images

Aug 5, 2025; Atlanta, Georgia, USA; Milwaukee Brewers starting pitcher Freddy Peralta (51) throws against the Atlanta Braves in the third inning at Truist Park. Mandatory Credit: Brett Davis-Imagn Images

Chicago Cubs vs Milwaukee Brewers

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The Chicago Cubs and St. Louis Cardinals meet Saturday in Game 1 NLDS MLB action at American Family Field. Here’s a Chicago Cubs vs Milwaukee Brewers Prediction. This article will include a Chicago Cubs vs Milwaukee Brewers Pick.

Chicago Cubs Betting Preview


The Chicago Cubs are coming off a 3-game series with the Padres. The Chicago Cubs are batting .258 on the season, have a .295 OBP, and a .404 slugging percentage. The Chicago Cubs pitching staff has a 1.67 ERA and a 0.85 WHIP. Nico Hoerner leads the Chicago Cubs with 4 hits and 1 RBI, while Michael Busch and Seiya Suzuki have combined for 7 hits and 2 RBI.

Matthew Boyd gets the ball for the Chicago Cubs, and he is 14-8 with a 3.21 ERA and 154 strikeouts this season. Boyd is 2-2 with a 1.10 ERA and 16 strikeouts in his postseason career. Boyd is 2-2 with a 9.00 ERA and 19 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview


The Milwaukee Brewers are 97-65 on the year and play for the first time since September 28. The Milwaukee Brewers are batting .258 on the season, have a .332 OBP, and a .403 slugging percentage. The Milwaukee Brewers pitching staff has a 3.58 ERA and a 1.23 WHIP. Brice Turang leads the Milwaukee Brewers with 168 hits and 81 RBI while Sal Frelick and Christian Yelich have combined for 303 hits and 166 RBI.

Freddy Peralta gets the ball for the Milwaukee Brewers, and he is 17-6 with a 2.70 ERA and 204 strikeouts this season. Peralta is 0-1 with a 4.00 ERA and 22 strikeouts in his postseason career. Peralta is 9-3 with a 3.21 ERA and 131 strikeouts in his career against the Chicago Cubs.

The Chicago Cubs @ Milwaukee Brewers Betting Trends: October 4, 2025


Why the Milwaukee Brewers will win

Why the Chicago Cubs will win

Total Runs Facts

Milwaukee Brewers Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Chicago Cubs vs Milwaukee Brewers Prediction


The Cubs looked sharp in their wild card series, and a part of me is thinking they could be a sneaky contender. However, the Brewers have been so consistent they’re just hard to bet against, especially at home with the rest advantage. Some still aren’t believers in the Brewers, but we’ve had 162 game sample size, folks. The Brewers are legit. Peralta also has been one of the best pitchers in baseball with his 2.70 ERA and 1.08 WHIP, and through 91.2 home innings, he has a 1.77 ERA and .192 allowed batting average. I can’t go against that. Give me the Brewers to draw first blood on Saturday.

Randy Chambers's Pick: Milwaukee Brewers

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