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Chicago Cubs vs Los Angeles Angels Prediction 8/23/2025 Today’s MLB Picks

Aug 22, 2025; Anaheim, California, USA; Chicago Cubs center fielder Pete Crow-Armstrong (4) crosses home plate after hitting a home run in the ninth inning as Los Angeles Angels relief pitcher Kenley Jansen (74) and catcher Logan O'Hoppe (14) and home plate umpire Adrian Johnson watch at Angel Stadium. Mandatory Credit: Kirby Lee-Imagn Images

Aug 22, 2025; Anaheim, California, USA; Chicago Cubs center fielder Pete Crow-Armstrong (4) crosses home plate after hitting a home run in the ninth inning as Los Angeles Angels relief pitcher Kenley Jansen (74) and catcher Logan O'Hoppe (14) and home plate umpire Adrian Johnson watch at Angel Stadium. Mandatory Credit: Kirby Lee-Imagn Images

MATCHUP Chicago Cubs Los Angeles Angels
Team Records 76-55 61-69
Where Angel Stadium, Anaheim, California
When Saturday, August 23, 2025
Time 09:38 PM EDT
TV FanDuel SN West

The Chicago Cubs and Los Angeles Angels meet Saturday in MLB action at Angel Stadium. Here’s a Chicago Cubs vs Los Angeles Angels Prediction. This article will include a Chicago Cubs vs Los Angeles Angels Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 74-55 on the year and play the Giants, Rockies, and Braves next. The Chicago Cubs are batting .248 on the season, have a .319 OBP, and a .426 slugging percentage. The Chicago Cubs pitching staff has a 3.79 ERA and a 1.20 WHIP. Nico Hoerner leads the Chicago Cubs with 135 hits and 49 RBI, while Pete Crow-Armstrong and Dansby Swanson have combined for 242 hits and 138 RBI.

Cade Horton gets the ball for the Chicago Cubs, and he is 7-4 with a 3.08 ERA and 70 strikeouts this season. This will be Horton’s first career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 61-67 on the year and play the Rangers, Astros, and Royals next. The Los Angeles Angels are batting .232 on the season, have a .305 OBP, and a .407 slugging percentage. The Los Angeles Angels pitching staff has a 4.66 ERA and a 1.43 WHIP. Nolan Schanuel leads the Los Angeles Angels with 123 hits and 49 RBI while Zach Neto and Taylor Ward have combined for 226 hits and 147 RBI.

Victor Mederos gets the ball for the Los Angeles Angels, and he is 0-1 with a 5.54 ERA and 10 strikeouts this season. This will be Mederos’ first career game against the Chicago Cubs.

Why the Los Angeles Angels will win

Why the Chicago Cubs will win

Los Angeles Angels Player Prop Facts

Chicago Cubs Player Prop Facts

Chicago Cubs vs Los Angeles Angels Prediction

The Cubs are not only the better team, but Horton has been ridiculous lately, allowing 15 hits and two runs in his last 31 innings. That’s just an elite stretch you shouldn’t be stepping in front of, honestly. Also, Mederos has pitched 21.1 MLB innings and has a 7.59 ERA and 2.11 WHIP. Up to this point, it’s fair to say Mederos is not a major league pitcher. This is a complete pitching mismatch. Give me the Cubs.

Randy Chambers's Pick: Chicago Cubs

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