Brewers vs Twins Prediction 5/16/2026 Today’s MLB Picks

In this article we will formulate a Brewers vs Twins prediction for this MLB game on Saturday, May 16th at Target Field in Minneapolis, Minnesota. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 25-17 this season after they won game one by a score of 3-2 on Friday night. Milwaukee trailed 2-1 in the seventh inning, but they scored two in the eighth to escape with the win. The Brewers recorded nine hits and they committed one error in the game, while they were led by Bauers, who went 2-4 with one RBI. Crow allowed three hits and one earned run over 5.0 innings, while Ashby got the win and Megill picked up the save. Prior to this series, Milwaukee won two out of three against the Padres and all three against the Yankees. 

This season, Milwaukee has a 3.32 ERA with a 1.22 WHIP and a .225 opponent batting average, while they have scored 212 runs with a .245 batting average and a .334 on base percentage. Brice Turang has led the Brewers with six home runs and 27 RBIs, while Jake Bauers has added six home runs and 22 RBIs. The projected starting pitcher for Milwaukee is Logan Henderson, who is 0-1 with a 4.15 ERA and a 0.92 WHIP over 13.0 innings pitched this season. 

Minnesota Twins Betting Preview

The Minnesota Twins are 20-25 this year after they lost game one by a score of 3-2 last night. Minnesota scored one run in the sixth and one in the seventh to take the lead, but their bullpen couldn’t hold on for the loss. The Twins recorded eight hits and they committed one error, while they were led by Lewis, who went 1-4 with one RBI in the game. Ryan allowed four hits and one earned run over 6.0 innings, while Morris picked up the loss in relief. Prior to this series, Minnesota won two out of three against the Marlins and two out of three against the Guardians. 

This season, Minnesota has a 4.43 ERA with a 1.35 WHIP and a .247 opponent batting average, while they have scored 213 runs with a .236 batting average and a .324 on base percentage. Byron Buxton has led the Twins with 15 home runs and 23 RBIs, while Ryan Jeffers has added six home runs and 25 RBIs. The projected starting pitcher for Minnesota is Connor Prielipp, who is 1-1 with a 3.32 ERA and a 1.00 WHIP over 19.0 innings pitched this year. 

Why the Minnesota Twins will win

• The underdogs have won each of the last six games between the Brewers and Twins at Target Field.
• The Brewers have lost five of their last six games as road favorites against American League opponents following a road win.
• The Twins have covered the run line in nine of their last 10 night games against the Brewers following a loss.
• The Brewers have failed to cover the run line in five of their last six games as favorites against American League opponents following a road win.

Why the Milwaukee Brewers will win

• The Twins have lost each of their last 10 Saturday games at Target Field.
• The road team has won nine of the last 10 games between the Brewers and Twins.
• The Twins have failed to cover the run line in each of their last 10 Saturday games at Target Field.
• The Brewers have covered the run line in each of their last six games at Target Field.
• The Twins have trailed after 5 innings in eight of their last 10 games at Target Field against opponents that held a winning record.

Total Runs Facts

• Each of the Brewers’ last four night games against American League opponents have gone UNDER the total runs line.
• Six of the Twins’ last seven night games against NL Central opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Brewers’ last five games as favorites against AL Central opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Twins’ last five night games.

Minnesota Twins Player Prop Facts

• Ryan Jeffers has hit a home run in three of his last four appearances with the Twins as underdogs against NL opponents.
• Victor Caratini has recorded two hits in each of his last four appearances with his team as a home underdog against NL Central opponents.

Milwaukee Brewers Player Prop Facts

• Gary Sanchez has hit a home run in seven of his last 16 appearances with his team as a favorite against AL opponents.
• Sal Frelick has recorded at least one hit in each of his last 10 road appearances against AL opponents.

Brewers vs Twins Prediction 

Milwaukee was able to rally in the later innings for the win on Friday night and they have won six of their last seven games. The Brewers are 10-8 on the road this year, while the Twins are 12-12 at home. Minnesota has won three of their last five games and they have allowed three runs or fewer in three of their last four. The Twins are starting Prielipp, who has allowed two earned runs in four straight starts, while Henderson has allowed two earned runs in each of his three outings. I think the pitching matchup is very even, so I will back the better overall team and take the Brewers again here.

David Racey's Pick: Brewers ML