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Brewers vs Reds Prediction 9/6/2026 Today’s MLB Picks

Sep 17, 2025; St. Louis, Missouri, USA; Cincinnati Reds shortstop Elly De La Cruz (44, left), Cincinnati Reds first baseman Spencer Steer (7, center), and Cincinnati Reds third baseman Sal Stewart (43) walk back to the dugout after Steer hit a three-rin home run in the fourth inning against the St. Louis Cardinals at Busch Stadium. Mandatory Credit: Tim Vizer-Imagn Images

Sep 17, 2025; St. Louis, Missouri, USA; Cincinnati Reds shortstop Elly De La Cruz (44, left), Cincinnati Reds first baseman Spencer Steer (7, center), and Cincinnati Reds third baseman Sal Stewart (43) walk back to the dugout after Steer hit a three-rin home run in the fourth inning against the St. Louis Cardinals at Busch Stadium. Mandatory Credit: Tim Vizer-Imagn Images

MATCHUP Milwaukee Brewers Cincinnati Reds
Team Records 88-55 68-74
Spread -1.5 100 +1.5 -120
Moneyline -162 +134
Total Over 9 (-106) Under 9 (-113)
Where Great American Ball Park, Cincinnati, Ohio
When Sunday, September 6, 2026
Time 12:10 PM EDT
TV MLB.TV
In this article we will formulate a Brewers vs Reds prediction for this MLB game on Sunday, September 6th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 88-55 this season after they split the first two games by scores of 10-7 and 3-5. In game two, Milwaukee led 2-1 in the third inning, but scored just one run in the last six innings for the loss. The Brewers recorded eight hits in the game and they were led by Lara, who went 0-4 with one RBI. May allowed five hits and two earned runs over 3.2 innings, while Ashby picked up the loss in relief. Prior to this series, Milwaukee split four games with the Cubs and won two out of three against the Rangers. 

This season, Milwaukee has a 3.51 ERA with a 1.18 WHIP and a .222 opponent batting average, while they have scored 718 runs with a .256 batting average and a .339 on base percentage. Jake Bauers has led the Brewers with 23 home runs and 76 RBIs, while Brice Turang has added 17 home runs and 82 RBIs. The projected starting pitcher for Milwaukee is Kyle Harrison, who is 10-4 with a 3.45 ERA and a 1.20 WHIP over 107.0 innings pitched this season. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 68-74 this year after they won game two by a score of 5-3 on Saturday. Cincinnati was tied 3-3 in the seventh, but they scored once in the seventh and once in the eighth for the win. The Reds recorded 12 hits and they committed one error in the game, while they were led by De La Cruz, who went 2-4 with one home run and one RBI. Abbott allowed three hits and one earned run over 4.0 innings, while Santillan got the win and Pagan picked up the save. Prior to this series, Cincinnati won two out of three against the Padres and two out of three against the Cubs. 

This season, Cincinnati has a 4.66 ERA with a 1.43 WHIP and a .252 opponent batting average, while they have scored 593 runs with a .229 batting average and a .308 on base percentage. Sal Stewart has led the Reds with 31 home runs and 106 RBIs, while Elly De La Cruz has added 22 home runs and 62 RBIs. The projected starting pitcher for Cincinnati is Brady Singer, who is 5-13 with a 4.83 ERA and a 1.45 WHIP over 141.2 innings pitched this year. 

Why the Cincinnati Reds will win

Why the Milwaukee Brewers will win

Total Runs Facts

Cincinnati Reds Player Prop Facts

Milwaukee Brewers Player Prop Facts

Matchup/League Facts

Brewers vs Reds Prediction 

Cincinnati was able to get the win on Saturday in game two and they have won three of their last four games. The Reds are 35-38 at home this year, while the Brewers are 41-30 on the road. Milwaukee has lost two of their last three games and they have allowed 5+ runs in three of their last four. The Brewers are starting Harrison, who has allowed 9, 1, 0, 3, and 0 earned runs in his last five stats, while Singer has allowed 3+ earned runs in five straight outings. Take the Brewers -1.5 here.

David Racey's Pick: Brewers -1.5

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