Brewers vs Reds Prediction 6/22/2026 Today’s MLB Picks

In this article we will formulate a Brewers vs Reds prediction for this MLB game on Monday, June 22nd at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 46-29 this season after they lost two out of three against the Braves by scores of 2-3, 3-4, and 9-4. In game three, Milwaukee trailed 1-0 in the first inning, but they scored the next eight runs to pull away in the win. The Brewers recorded 13 hits in the game and they were led by Contreras, who went 4-5 with one home run and three RBIs. Gasser allowed four hits and two earned runs over 6.0 innings for the win, while Patrick picked up the nine out save. Prior to that series, Milwaukee won two out of three against the Guardians and two out of three against the Phillies. 

This season, Milwaukee has a 3.45 ERA with a 1.19 WHIP and a .223 opponent batting average, while they have scored 397 runs with a .256 batting average and a .340 on base percentage. Jake Bauers has led the Brewers with 13 home runs and 46 RBIs, while Brice Turang has added 11 home runs and 47 RBIs. The projected starting pitcher for Milwaukee is Brandon Woodruff, who is 2-1 with a 3.60 ERA and a 1.03 WHIP over 30.0 innings pitched this season. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 37-39 this year after they won two out of three against the Yankees by scores of 0-5, 10-2, and 4-1. In game three, Cincinnati scored three runs in the third inning and one in the ninth to get the win. The Reds recorded seven hits in the game and they were led by Stephenson, who went 1-4 with one home run and three RBIs. Burns allowed five hits and one earned run over 5.0 innings for the win, while Santillan picked up the save. Prior to that series, Cincinnati won two out of three against the Mets, but lost two out of three against the Diamondbacks before that. 

This season, Cincinnati has a 4.58 ERA with a 1.46 WHIP and a .250 opponent batting average, while they have scored 325 runs with a .229 batting average and a .311 on base percentage. Sal Stewart has led the Reds with 14 home runs and 53 RBIs, while Elly De La Cruz has added 12 home runs and 37 RBIs. The projected starting pitcher for Cincinnati is Brady Singer, who is 3-6 with a 5.32 ERA and a 1.61 WHIP over 66.0 innings pitched this year. 

Why the Cincinnati Reds will win

• The Brewers have lost each of their last six Monday night games as road favorites against NL Central opponents.
• The Reds have won each of their last five Monday night games as home underdogs against NL Central opponents.
• The underdogs have covered the run line in 14 of the Brewers’ last 16 games at Great American Ball Park.
• The Brewers have failed to cover the run line each of their last five games against NL Central opponents that held a losing record.
• The Reds have led after 5 innings in each of their last three night games against National League opponents.
• The Brewers have trailed after 3 innings in three of their last four games as road favorites.

Why the Milwaukee Brewers will win

• The Brewers have won 14 of their last 15 night games against National League opponents following a road win.
• The Reds have lost each of their last six home games against the Brewers following a win.
• The Brewers have covered the run line in eight of their last nine road games against National League opponents after playing the previous day.
• The Reds have failed to cover the run line in six of their last seven games at Great American Ball Park following a win.
• The Reds have trailed after 3 innings in four of their last five games as home underdogs against NL Central opponents.

Total Runs Facts

• Each of the Brewers’ last four games as favorites against NL Central opponents have gone UNDER the total runs line.
• Each of the Reds’ last three night games against NL Central opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in each of the last five games between the Brewers and Reds.
• There has been at least one run scored in the first inning in five of the Brewers’ last six games as road favorites.

Cincinnati Reds Player Prop Facts

• JJ Bleday has hit a home run in three of the Reds’ last four Monday games.
• Brady Singer has recorded five or more strikeouts in five of his last six appearances with the Reds as underdogs.
• Elly De La Cruz has recorded a hit in each of the Reds’ last seven games as underdogs against the Brewers.

Milwaukee Brewers Player Prop Facts

• Jackson Chourio has hit a home run in each of the Brewers’ last two games against opponents that held a losing record.
• Brandon Woodruff has recorded six or more strikeouts in each of his last six appearances against the Reds.
• Brice Turang has recorded at least one hit in each of his last 11 appearances against NL opponents that held a losing record.
• Brandon Woodruff has recorded a win in seven of his last eight road appearances against opponents that held a losing record.

Matchup/League Facts

• The Reds rank 28th in the league for batting average this season (.229).
• The Reds rank 28th in the league for walks allowed this season (345).
• The Brewers rank 2nd in the league for opponent batting average this season (.223).
• The Brewers rank 2nd in the league for home runs allowed this season (72).

Brewers vs Reds Prediction

Cincinnati is coming off of a huge series win against the Yankees and they have won three of their last five games. The Reds are 19-19 at home this year, while the Brewers are 21-14 on the road. Milwaukee has lost three of their last four games, but they avoided the sweep with a win on Sunday. The Brewers are starting Woodruff, who is making his first appearance since April, while Singer has allowed two earned runs or fewer in three straight starts. I don’t like backing pitchers after long injuries, so give me the Reds here.

David Racey's Pick: Reds ML