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Brewers vs Pirates Prediction 9/15/2026 Today’s MLB Picks

May 25, 2026; Milwaukee, Wisconsin, USA;  Milwaukee Brewers pitcher Jacob Misiorowski (32) throws a pitch during the first inning against the St. Louis Cardinals at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

May 25, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers pitcher Jacob Misiorowski (32) throws a pitch during the first inning against the St. Louis Cardinals at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

MATCHUP Milwaukee Brewers Pittsburgh Pirates
Team Records 93-57 75-75
Spread -1.5 -136 +1.5 113
Moneyline -249 +201
Total Over 7.5 (-117) Under 7.5 (-103)
Where PNC Park, Pittsburgh, Pennsylvania
When Tuesday, September 15, 2026
Time 06:40 PM EDT
TV MLB.TV
In this article we will formulate a Brewers vs Pirates prediction for this MLB game on Tuesday, September 15th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 93-57 this season after they won two out of three against the Reds by scores of 20-0, 13-9, and 3-4. In game three, Milwaukee led 2-0 in the second inning, but scored just one run in the last seven innings for the loss. The Brewers recorded six hits in the game and they were led by Ortiz, who went 1-3 with one home run and two RBIs. Gasser allowed three hits and one earned run over 5.0 innings, while Uribe picked up the loss in relief. Prior to that series, Milwaukee swept the Cubs in three games, but lost two out of three against the Reds before that. 

This season, Milwaukee has a 3.57 ERA with a 1.19 WHIP and a .223 opponent batting average, while they have scored 778 runs with a .259 batting average and a .341 on base percentage. Jake Bauers has led the Brewers with 26 home runs and 83 RBIs, while Brice Turang has added 19 home runs and 92 RBIs. The projected starting pitcher for Milwaukee is Jacob Misiorowski, who is 14-5 with a 1.95 ERA and a 0.80 WHIP over 161.1 innings pitched this season. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 75-75 this year after they lost two out of three against the Cubs by scores of 2-12, 3-4, and 4-3. In game three, Pittsburgh scored three runs in the sixth inning to get the narrow win. The Pirates recorded nine hits in the game and they were led by Lowe, who went 1-2 with two RBIs. Chandler allowed five hits and three earned runs over 5.1 innings for the win, while Montgomery picked up the save. Prior to that series, Pittsburgh swept the White Sox in three games and won two out of three against the Angels. 

This season, Pittsburgh has a 4.18 ERA with a 1.30 WHIP and a .237 opponent batting average, while they have scored 718 runs with a .253 batting average and a .330 on base percentage. Brandon Lowe has led the Pirates with 29 home runs and 85 RBIs, while Ryan O’Hearn has added 18 home runs and 72 RBIs. The projected starting pitcher for Pittsburgh is Lake Bachar, who is 1-3 with a 3.52 ERA and a 1.10 WHIP over 79.1 innings pitched this year. 

Why the Pittsburgh Pirates will win

Why the Milwaukee Brewers will win

Total Runs Facts

Pittsburgh Pirates Player Prop Facts

Milwaukee Brewers Player Prop Facts

Brewers vs Pirates Prediction 

Milwaukee had their winning streak snapped on Sunday in game three against the Reds, but they have scored 8+ runs in three of their last four games. The Brewers are 41-31 on the road this year, while the Pirates are 38-34 at home. Pittsburgh has won three of their last five games, but they have scored three or fewer in three of their last four. The Pirates are starting Bachar, who will be an opener, while Misiorowski has allowed two earned runs or fewer in four of his last five starts. I don’t like the value with Milwaukee here, so I will take a shot on the Pirates +1.5 at plus money.

David Racey's Pick: Pirates +1.5

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