Brewers vs Phillies Prediction 9/22/2026 Today’s MLB Picks

In this article we will formulate a Brewers vs Phillies prediction for this MLB game on Tuesday, September 22nd at Citizens Bank Park in Philadelphia, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 98-58 this season after they swept the Orioles in three games by scores of 6-5, 1-0, and 3-0. In game three, Milwaukee took the lead in the second inning and never gave it up in the shutout win. The Brewers recorded six hits in the game and they were led by Pratt, who went 2-3 with two RBIs. Misiorowski allowed one hit and zero earned runs over 3.0 innings, while Hall picked up the win in relief. Prior to that series, Milwaukee won two out of three against the Pirates and two out of three against the Reds. 

This season, Milwaukee has a 3.54 ERA with a 1.19 WHIP and a .223 opponent batting average, while they have scored 802 runs with a .258 batting average and a .341 on base percentage. Jake Bauers has led the Brewers with 26 home runs and 83 RBIs, while Brice Turang has added 19 home runs and 93 RBIs. The projected starting pitcher for Milwaukee is Dustin May, who is 7-9 with a 4.61 ERA and a 1.32 WHIP over 140.2 innings pitched this season. 

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 86-70 this year after they split four games with the Mets by scores of 3-0, 3-6, 3-10, and 7-2. In game four, Philadelphia had their lead cut to 4-2 in the seventh inning, but they scored three in the eighth to seal the win. The Phillies recorded seven hits in the game and they were led by Crawford, who went 1-4 with three RBIs. Sanchez allowed six hits and two earned runs over 6.1 innings for the win, while McFarlane picked up a hold. Prior to that series, Philadelphia split two games with the Nationals and lost two out of three against the Braves. 

This season, Philadelphia has a 4.00 ERA with a 1.29 WHIP and a .248 opponent batting average, while they have scored 697 runs with a .241 batting average and a .312 on base percentage. Kyle Schwarber has led the Phillies with 45 home runs and 95 RBIs, while Bryce Harper has added 28 home runs and 85 RBIs. The projected starting pitcher for Philadelphia is Zack Wheeler, who is 13-5 with a 2.99 ERA and a 1.06 WHIP over 150.1 innings pitched this year. 

Why the Philadelphia Phillies will win

• The Phillies have won seven of their last eight games at Citizens Bank Park against NL Central opponents that held a winning record.
• The Brewers have lost three of their last four road games against NL opponents following a win.
• The Brewers have failed to cover the run line in each of their last four games against NL opponents following a road win.
• The favorites have covered the run line in each of the Phillies’ last three games.
• The Brewers have trailed after 3 innings in three of their last four road games against NL opponents that held a winning record.
• The Brewers have trailed after 5 innings in three of their last four road games against NL opponents that held a winning record.

Why the Milwaukee Brewers will win

• The Brewers have won each of their last five games as underdogs against the Phillies.
• The Phillies have lost eight of their last 10 games as favorites against NL Central opponents following a road win.
• The Brewers have covered the run line in each of their last seven games against the Phillies following a road win.
• The Phillies have failed to cover the run line in nine of their last 10 games as favorites against NL Central opponents following a road win.
• The Phillies have trailed after 5 innings in three of their last four night games against opponents that held a winning record.

Total Runs Facts

• Four of the Phillies’ last five home games against NL Central opponents have gone OVER the total runs line.
• Four of the Brewers’ last five night games against NL opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in each of the Brewers’ last six road games.
• There has been no run scored during the first inning in each of the Phillies’ last eight Tuesday night games against NL Central opponents.

Philadelphia Phillies Player Prop Facts

• Kyle Schwarber has hit a home run in five of the Phillies’ last six games as home favorites against NL opponents.
• Zack Wheeler has recorded seven or more strikeouts in each of his last 11 appearances with the Phillies as home favorites against NL opponents.
• Zack Wheeler has recorded a win in three of his last four appearances.
• Bryan De La Cruz has recorded at least one hit in each of his last 12 appearances with his team as a home favorite against NL Central opponents.

Milwaukee Brewers Player Prop Facts

• Jackson Chourio has hit a home run in three of the Brewers’ last four night games against NL opponents that held a winning record.
• Dustin May has recorded five or more strikeouts in each of his last seven Tuesday appearances in night games.
• Andrew Vaughn has recorded at least one hit in each of his last 13 road appearances against NL East opponents.

Brewers vs Phillies Prediction 

Milwaukee comes into this matchup after winning four of their last five games and they have allowed zero runs in their last two games. The Brewers are 46-32 on the road this year, while the Phillies are 41-34 at home. Philadelphia has won three of their last five games, but they have scored three runs in four of those five. The Phillies are starting Wheeler, who has allowed one earned run or fewer in four straight starts, while May has allowed 3, 0, 2, and 4 earned runs in his last four outings. Take the Phillies to win here.

David Racey's Pick: Phillies ML