Boston Red Sox vs Toronto Blue Jays Prediction 5/1/25 MLB Picks

The Boston Red Sox and the Toronto Blue Jays meet Thursday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

Tanner Houck will get the start for the Red Sox, and Houck is 0-2 with a 7.58 ERA and 24 strikeouts this season. In his last five starts against Toronto, Houck is 1-0 with a 3.30 ERA and 19 strikeouts. Jose Berrios will get the start for the Blue Jays here and is 1-1 with a 4.24 ERA and 28 strikeouts this season. In his last five starts against Boston, Berrios is 4-1 with a 2.70 ERA and 30 strikeouts.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back after ending up with a 7-6 loss at the hands of the Blue Jays on Wednesday to fall to 17-15 on the year. After this series, the Red Sox will head back to Fenway for a series against the Minnesota Twins.

Red Sox Have Three-Game Win Streak Snapped

Alex Bregman leads the Red Sox with 40 hits, including a team-high 11 doubles along with 6 home runs and 23 RBIs, while Rafael Devers has added 25 hits with 8 doubles, 5 home runs and 18 RBIs this season. Trevor Story added 32 hits with 5 home runs, 16 RBIs, and 6 stolen bases, while Jarren Duran has 36 hits with 8 doubles, 3 triples, 2 home runs, 16 RBIs, and a team-high 9 stolen bases. Kristian Campbell added 31 hits with 8 doubles, 4 homers, and 12 RBIs, while Wilyer Abreu has 6 home runs with 21 RBIs and 4 stolen bases, and Ceddanne Rafaela has 2 homers, 15 RBIs, and 6 stolen bases this season.

Why the Boston Red Sox will win

• The Blue Jays have lost each of their last six games as favorites against AL East opponents following a win.
• The Red Sox have won eight of their last 10 games as underdogs against AL East opponents following a road loss.
• The Blue Jays have failed to cover the run line in each of their last 11 home games against AL East opponents following a home win.
• The Red Sox have covered the run line in 11 of their last 12 games as underdogs against AL East opponents following a road loss.

Boston Red Sox Player Prop Facts

• Alex Bregman has hit at least one home run in four of his last five road appearances against AL East opponents.
• Rafael Devers has recorded an RBI in seven of the Red Sox’s last eight games against AL opponents.
• Rafael Devers has scored at least one run in each of the Red Sox’s last six night games.
• Jarren Duran has recorded at least one Single in seven of his last eight road appearances against the Blue Jays after playing the previous day.
• Alex Bregman has recorded at least one hit in each of the Red Sox’s last 10 games against AL opponents.
• Alex Bregman ranks 3rd in the league in Hits (41) this season.

Toronto Blue Jays Recap

The Toronto Blue Jays will be out to add on to their win over the Red Sox on Wednesday to improve their record to 14-16 this season. After this series, the Blue Jays will square off against the Cleveland Guardians at home.

Blue Jays Snap Three-Game Losing Streak

George Springer has 26 hits and Bo Bichette has 36 hits, with Springer adding 2 home runs, a triple, 7 doubles, and 12 RBIs while Bichette has 9 doubles and 13 RBIs. Andres Gimenez has added 18 hits with 4 doubles and a team-high 3 home runs and 8 RBIs this season, along with 8 stolen bases, while Anthony Santander has a team-high 30 strikeouts so far this season. Vladimir Guerrero Jr. also has 3 homers, 6 doubles, and 14 RBIs, while Springer also has a .313 batting average up to this point in the year.

Why the Toronto Blue Jays will win

• The Red Sox have lost each of their last six road games after going to extra innings.
• The Blue Jays have won each of their last six Thursday night games.
• The Blue Jays have covered the run line in each of their last five games as home favorites.
• The Red Sox have failed to cover the run line in each of their last four games against American League opponents after going to extra innings.

Toronto Blue Jays Player Prop Facts

• Daulton Varsho has hit a home run in two of his last three appearances against AL opponents that held a winning record.
• Jose Berrios has recorded a win in each of his last four appearances against the Red Sox.
• Alejandro Kirk has recorded at least one RBI in four of his last five home appearances against AL opponents.
• Jose Berrios has recorded six or more strikeouts in six of his last seven home appearances against AL East opponents that held a winning record.
• Bo Bichette has scored a run in each of his last seven Thursday night appearances against AL teams that held a winning record.
• Bo Bichette has recorded at least one Single in each of the Blue Jays’ last eight home games against AL opponents.
• Alejandro Kirk has recorded at least one hit in each of his last eight home appearances against the Red Sox after playing the previous day.
• Bo Bichette ranks T5th in the league in Hits (38) this season.

Total Runs Facts

• Each of the Blue Jays’ last six games as favorites have gone UNDER the total runs line.
• Each of the Red Sox’s last six night games against American League opponents have gone OVER the total runs line.

Boston Red Sox vs. Toronto Blue Jays Prediction

I’m on the Blue Jays here. Toronto let it get a little bit dicey on Wednesday, but in the end, the offense came through in the walk-off win, and now the Jays get a crack at Tanner Houck, who has been terrible on the road this season. Berrios has had a lot of success against the Red Sox, including a win a few weeks ago with seven innings of one-run ball. I’ll back Toronto at home for the series win here.

Chris Ruffolo's Pick: Toronto Blue Jays -112