Boston Red Sox vs Toronto Blue Jays Prediction 4/29/2026 Today’s MLB Picks

In this article, we will formulate a Red Sox vs Blue Jays Prediction for this MLB matchup on Wednesday, April 29th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Toronto Blue Jays Preview

The Toronto Blue Jays have a 13-16 record this season and are sitting in the fourth place of the AL East. They have a 9-8 home record and are coming off a 3-0 home win against the Red Sox. Their previous three games were a 0-5 home loss against the Red Sox, a 4-2 and a 5-3 home win against the Guardians.

The Blue Jays have a .248 batting average this season, .309 OBP and .375 Slugging percentage. Toronto’s pitching staff has a 4.31 ERA and 1.30 WHIP. Vladimir Guerrero Jr. is the team’s best hitter with a .340 batting average. Andres Gimenez leads the team in RBI with 16, and Kazuma Okamoto adds a team‑high 5 home runs.

Eric Lauer (L) is the projected starting pitcher for the Blue Jays, and he has a 1-3 record, 6.75 ERA and 1.54 WHIP.

Boston Red Sox Preview

The Boston Red Sox have a 12-18 record this season and are sitting in the fifth place of the AL East. They have a 7-10 away record and are coming off a 0-3 road loss against the Blue Jays. Their previous three games were a 5-0 road win against the Blue Jays, a 5-3 and a 17-1 road win against the Orioles.

The Red Sox have a .231 batting average this season, .310 OBP and .350 Slugging percentage. Boston’s pitching staff has a 4.20 ERA and 1.30 WHIP. Wilyer Abreu is the team’s best hitter with a .297 batting average. Willson Contreras leads the team in RBI with 19, also adding a team‑high 6 home runs.

Brayan Bello (R) is the projected starting pitcher for the Red Sox, and he has a 1-3 record, 9.00 ERA and 2.27 WHIP.

Boston Red Sox @ Toronto Blue Jays Betting Trends: April 29, 2026

• Probable Starting Pitcher: Eric Lauer      Record this season: 1-3      ERA: 6.75
• Home Record: 1-1
• Last 5 against Red Sox: 1-0

Why the Toronto Blue Jays will win

• The Blue Jays have won each of their last seven day games against AL East opponents following a home win.
• The Red Sox have lost each of their last five day games at Rogers Centre following a loss.
• The Blue Jays have covered the run line in seven of their last eight home games against AL East opponents.
• The Red Sox have failed to cover the run line in six of their last seven games as underdogs following a loss.
• The Blue Jays have won the first inning in three of their last four day games at Rogers Centre.
• The Blue Jays have led after 3 innings in each of their last four day games against AL East opponents.
• The Blue Jays have led after 5 innings in seven of their last eight home games against American League opponents that held a losing record.

• Probable Starting Pitcher: Brayan Bello      Record this season: 1-3      ERA: 9.00
• Road Record: 1-2
• Last 5 against Blue Jays: 1-3

Why the Boston Red Sox will win

• The Blue Jays have lost each of their last four games as favorites against the Red Sox following a win.
• The Red Sox have won four of their last five games as road underdogs against AL East opponents following a road loss.
• The Blue Jays have failed to cover the run line in each of their last seven games as favorites against the Red Sox following a win.
• The Red Sox have covered the run line in 13 of their last 15 games as road underdogs against AL East opponents following a road loss.
• The Blue Jays have lost the first inning in three of their last four day games against opponents that held a losing record.
• The Blue Jays have trailed after 3 innings in seven of their last eight day games against American League opponents.
• The Red Sox have led after 5 innings in each of their last four road day games.

Total Runs Facts

• Each of the Blue Jays’ last four games as favorites against the Red Sox have gone UNDER the total runs line.
• Each of the Red Sox’s last four day games against American League opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last 11 Wednesday games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the last six games between the Red Sox and Blue Jays at Rogers Centre.

Toronto Blue Jays Player Prop Facts

• George Springer has recorded at least one hit in each of his last 13 home appearances against AL opponents that held a losing record.
• Alejandro Kirk has hit at least one home run in each of his last three appearances with the Blue Jays as favorites against AL East opponents.
• Vladimir Guerrero Jr. ranks 2nd amongst qualified players for Batting Average (.340) this season.

Boston Red Sox Player Prop Facts

• Willson Contreras has hit a home run in three of the Red Sox’s last four day games.
• Isiah Kiner-Falefa has recorded at least one hit in each of his 13 previous appearances with his team as a road underdog against the Blue Jays.

Matchup/League Facts

• The Blue Jays rank 1st in the league for strikeouts against this season (205).
• The Blue Jays rank 2nd in the league for strikeouts this season (282).
• The Red Sox rank 29th in the league for slugging percentage this season (.350).
• The Red Sox rank T28th in the league for home runs this season (20).

Red Sox vs Blue Jays Prediction

Both teams are tied 4-4 in their last 8 meetings and are 3-3 in their last 6 meetings in Toronto.

In this Red Sox vs Blue Jays Prediction, the Blue Jays are coming as -135 home favorites. Toronto won yesterday by 3-0, bouncing back from Monday’s 5-0 shutout but I don’t trust either pitcher in this matchup. They both have a combined 15.75 ERA and Bello cannot catch a break this season, coming off his worst start of the season. Lauer has also given up 10 runs in his last two starts and Toronto’s bullpen has been shaky, so I expect some runs in this one. Take the over 8.

Nikos Lagouretos's Pick: Over 8