Boston Red Sox vs Toronto Blue Jays Prediction 4/27/2026 Today’s MLB Picks

Nikos Lagouretos

3 hours ago

Mar 28, 2026; Toronto, Ontario, CAN; Toronto Blue Jays pitcher Dylan Cease (84) pitches to the Athletics during the first inning at Rogers Centre. Mandatory Credit: Kevin Sousa-Imagn Images

MATCHUP	Boston Red Sox	Toronto Blue Jays
Team Records	11-17	12-15
Spread	+1.5 -186	-1.5 153
Moneyline	+119	-143
Total	Over 7 (-120)	Under 7 (100)
Where	Rogers Centre, Toronto, Ontario
When	Monday, April 27, 2026
Time	07:07 PM EDT
TV	MLB.TV

In this article, we will formulate a Red Sox vs Blue Jays Prediction for this MLB matchup on Monday, April 27th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Toronto Blue Jays Preview

The Toronto Blue Jays have a 12-15 record this season and are sitting in the fourth place of the AL East. They have a 8-7 home record and are coming off a 4-2 home win against the Guardians. Their previous three games were a 5-3 win and an 8-6 loss at home against the Guardians, and a 3-7 loss on the road against the Angels.

The Blue Jays have a .255 batting average this season, .314 OBP and .386 Slugging percentage. Toronto’s pitching staff has a 4.45 ERA and 1.32 WHIP. Vladimir Guerrero Jr. is the team’s best hitter with a .340 batting average. Andres Gimenez leads the team in RBI with 16, and Kazuma Okamoto adds a team‑high 5 home runs.

Dylan Cease (R) is the projected starting pitcher for the Blue Jays, and he has a 1-0 record, 2.10 ERA and 1.29 WHIP.

Boston Red Sox Preview

The Boston Red Sox have a 11-17 record this season and are sitting in the fifth place of the AL East. They have a 6-9 away record and are coming off a 5-3 road win against the Orioles. Their previous three games were a 17-1 win, a 10-3 loss on the road against the Orioles, and a 2-4 home loss against the Yankees.

The Red Sox have a .233 batting average this season, .313 OBP and .356 Slugging percentage. Boston’s pitching staff has a 4.38 ERA and 1.34 WHIP. Wilyer Abreu is the team’s best hitter with a .298 batting average. Willson Contreras leads the team in RBI with 19, also adding a team‑high 6 home runs.

Ranger Suarez (L) is the projected starting pitcher for the Red Sox, and he has a 1-2 record, 4.00 ERA and 1.15 WHIP.

Boston Red Sox @ Toronto Blue Jays Betting Trends: April 27, 2026

Probable Starting Pitcher: Dylan Cease Record this season: 1-0 ERA: 2.10
Home Record: 0-0
Last 5 against Red Sox: 1-1

Why the Toronto Blue Jays will win

The Blue Jays have won each of their last nine home games against American League opponents that held a losing record.
The Red Sox have lost each of their last six night games against AL East opponents.
The Red Sox have failed to cover the run line in each of their last 10 night games against American League opponents.
The Blue Jays have covered the run line in each of their last six home games against AL East opponents.
The Blue Jays have led after 5 innings in each of their last six home games against American League opponents that held a losing record.
The Blue Jays have won the first inning in four of their last five games against AL East opponents.
The Blue Jays have led after 3 innings in each of their last four home games against AL East opponents.

Probable Starting Pitcher: Ranger Suarez Record this season: 1-2 ERA: 4.00
Road Record: 1-1
Last 5 against Blue Jays: 1-0

Why the Boston Red Sox will win

The Blue Jays have lost each of their last three games as favorites against the Red Sox following a win.
The Red Sox have won 10 of their last 12 games as underdogs against the Blue Jays following a win.
The Blue Jays have failed to cover the run line in each of their last six games as favorites against the Red Sox following a win.
The Red Sox have covered the run line in 15 of their last 18 games as underdogs against the Blue Jays.
The Blue Jays have trailed after 5 innings in five of their last six games against opponents that held a losing record.
The Blue Jays have lost the first inning in three of their last four night games at Rogers Centre.
The Blue Jays have trailed after 3 innings in each of their last four home night games.

Total Runs Facts

Ten of the Red Sox’s last 11 road games after playing the previous day have gone OVER the total runs line.
Five of the Blue Jays’ last six home games have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Blue Jays’ last 11 games as favorites.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Red Sox’s last 12 games as road underdogs against AL East opponents.

Toronto Blue Jays Player Prop Facts

Dylan Cease has recorded eight or more strikeouts in each of his last three home appearances.
George Springer has recorded at least one hit in each of his last 14 appearances in night games against teams that held a losing record.
Alejandro Kirk has hit at least one home run in each of the Blue Jays’ last three games as favorites against AL East opponents.
Ernie Clement ranks T3rd in the league in Hits (36) this season.

Boston Red Sox Player Prop Facts

Roman Anthony has hit a home run in three of his last four appearances in night games against teams that held a losing record.
Ranger Suarez has recorded five or more strikeouts in each of his last four road appearances against opponents that held a losing record.
Ranger Suarez has recorded a win in three of his last four appearances with his team as a road underdog .
Isiah Kiner-Falefa has recorded at least one hit in each of his 13 previous appearances with his team as a road underdog against the Blue Jays.

Matchup/League Facts

The Blue Jays rank 1st in the league for strikeouts against this season (188).
The Blue Jays rank 28th in the league for steals this season (11).
The Red Sox rank T28th in the league for home runs this season (19).
The Red Sox rank 28th in the league for slugging percentage this season (.356).

Red Sox vs Blue Jays Prediction

Both teams are tied 5-5 in their last 10 meetings and are 3-3 in their last 6 meetings in Toronto.

In this Red Sox vs Blue Jays Prediction, the Blue Jays are coming as -140 home favorites. Both teams have been underwhelming this season with negative records so far but both have back-to-back wins. The Jays have the pitching advantage as Cease takes the mound and goes up against Ranger Suarez. Cease has been excellent this season and even better at home with a 1.74 home ERA, while Suarez has been extremely unstable, switching from a shutout to a 4-earned run start and has a 4.99 expected ERA. I don’t trust the Red Sox with Suarez on the mound on the road, so I will take the Jays to get it done at home in this one.