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Boston Red Sox vs St. Louis Cardinals Prediction 4/10/2026 Today’s MLB Picks

Apr 8, 2026; Boston, Massachusetts, USA; Wally the Boston Red Sox mascot celebrates the team's victory against the Milwaukee Brewers at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images

Apr 8, 2026; Boston, Massachusetts, USA; Wally the Boston Red Sox mascot celebrates the team's victory against the Milwaukee Brewers at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images

MATCHUP Boston Red Sox St. Louis Cardinals
Team Records 4-8 7-5
Spread -1.5 119 +1.5 -143
Moneyline -149 +123
Total Over 7.5 (-105) Under 7.5 (-115)
Where Busch Stadium, St. Louis, Missouri
When Friday, April 10, 2026
Time 08:15 PM EDT
TV MLB.TV
The Boston Red Sox and St. Louis Cardinals meet Friday in MLB action at Busch Stadium. Here’s a Boston Red Sox vs. St. Louis Cardinals Prediction. This article will include a Boston Red Sox vs. St. Louis Cardinals Pick.

Boston Red Sox Betting Preview


The Boston Red Sox are 4-8 on the year and play the Tigers and Twins next. The Boston Red Sox are batting. 226 on the season, have a .310 OBP, and have a .356 slugging percentage. The Boston Red Sox pitching staff has a 4.19 ERA and a 1.35 WHIP. Wilyer Abreu leads the Boston Red Sox with 18 hits and 9 RBI, while Ceddanne Rafaela and Willson Contreras have combined for 21 hits and 9 RBI.

Connelly Early gets the ball for the Boston Red Sox, and he is 0-0 with a 2.89 ERA and 10 strikeouts this season. This will be Early’s first career game against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 7-5 on the year and play the Guardians and Astros next. The St. Louis Cardinals are batting .226 on the season and have a .324 OBP, and a .361 slugging percentage. The St. Louis Cardinals pitching staff has a 4.95 ERA and a 1.52 WHIP. Jordan Walker leads the St. Louis Cardinals with 13 hits and 12 RBI while Alec Burleson and JJ Wetherholt have combined for 23 hits and 15 RBI.

Dustin May gets the ball for the St. Louis Cardinals, and he is 0-2 with a 15.95 ERA and 7 strikeouts this season. This will be May’s second career game against the Boston Red Sox.

Why the St. Louis Cardinals will win

Why the Boston Red Sox will win

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Boston Red Sox vs St. Louis Cardinals Prediction


The Red Sox are coming off a couple of wins and maybe that has a carryover effect. The Red Sox have life for the first time this season. Early has been solid through 9.1 innings. We can’t say the same for May through 7.1 innings, as he’s allowed 17 hits and 13 runs. Maybe May finds his footing, as he is a World Series champion and was a key piece in the Dodgers’ rotation. I just need to see it. I can’t get behind May and his struggles right now. The price is reasonable. Give me the Red Sox on Friday night.

Randy Chambers's Pick: Boston Red Sox

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