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Boston Red Sox vs Seattle Mariners Prediction 6/21/2026 Today’s MLB Picks

May 22, 2026; Kansas City, Missouri, USA; Seattle Mariners pitcher Logan Gilbert (36) pitches during the first inning against the Kansas City Royals at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

May 22, 2026; Kansas City, Missouri, USA; Seattle Mariners pitcher Logan Gilbert (36) pitches during the first inning against the Kansas City Royals at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

MATCHUP Boston Red Sox Seattle Mariners
Team Records 31-43 39-39
Spread +1.5 -205 -1.5 168
Moneyline +105 -126
Total Over 6.5 (-114) Under 6.5 (-105)
Where T-Mobile Park, Seattle, Washington
When Sunday, June 21, 2026
Time 04:10 PM EDT
TV MLB.TV

In this article, we will formulate a Red Sox vs Mariners Prediction for this MLB matchup on Sunday, June 21st in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 39-39 record this season and are sitting in the 1st place of the AL West. They have a 21-19 home record and are coming off a 1-5 home defeat against the Red Sox. They will face the Pirates and the Guardians next.

The Mariners have a .232 batting average this season, .313 OBP and .388 Slugging percentage. Seattle’s pitching staff has a 3.66 ERA and 1.18 WHIP. Randy Arozarena is the team’s best hitter with a .291 batting average. Julio Rodriguez leads the team in RBI with 37, while Luke Raley adds a team-high 14 home runs.

Logan Gilbert (R) is the projected starting pitcher for the Mariners, and he has a 5-4 record, 3.43 ERA and 1.03 WHIP.

Boston Red Sox Preview

The Boston Red Sox have a 31-43 record this season and are sitting in the 5th place of the AL East. They have a 19-18 road record and are coming off a 5-1 road win against the Mariners. They will face the Rockies and the Yankees next.

The Red Sox have a .244 batting average this season, .312 OBP and .382 Slugging percentage. Boston’s pitching staff has a 3.86 ERA and 1.26 WHIP. Willson Contreras is the team’s best hitter with a .286 batting average, also leading the team in RBI with 44 and adding a team-high 16 home runs.

Payton Tolle (L) is the projected starting pitcher for the Red Sox, and he has a 3-4 record, 2.93 ERA and 1.06 WHIP.

Boston Red Sox @ Seattle Mariners Betting Trends: June 21, 2026

Why the Seattle Mariners will win

Why the Boston Red Sox will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Red Sox vs Mariners Prediction

The Red Sox have won their last three meetings against the Mariners, all of them on the road.

In this Red Sox vs Mariners, the Mariners are coming as -150 home favorites. I like the pitching in this matchup, as both starters have a combined 6.30 ERA and Gilbert has been -red-hot lately, with just two earned runs in four of his last five starts. The Mariners have been struggling against lefties and both teams have top-6 bullpens, so I expect a low-scoring affair. Take the under 6.5 in this one.

Nikos Lagouretos's Pick: Under 6.5

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