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Boston Red Sox vs Detroit Tigers Prediction 5/13/25 MLB Picks

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Detroit Tigers (27-15) vs Boston Red Sox (22-21)

Game Info: Tuesday, May 13, 2025 at 6:40 pm (Comerica Park)

The Line: Betting Odds: Detroit Tigers -102 / Boston Red Sox -118 — Over/Under: 8.5

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The Boston Red Sox and the Detroit Tigers meet Tuesday in MLB action from Comerica Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Detroit Tigers prediction.

Starting Pitching Matchup

The Boston Red Sox will send out Brayan Bello for the start here, and Bello is 2-0 with a 2.01 ERA and 13 strikeouts. In his career, Bello is 0-1 with a 6.55 ERA and 10 strikeouts against Detroit. The Detroit Tigers will send out Tyler Holton for the start here, and Holton is 2-2 with a 3.12 ERA and 17 strikeouts this season. This will be Holton’s first career start against Boston.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from their series-opening 14-2 loss at the hands of the Tigers on Monday to slip to 22-21 on the year. After this series, the Red Sox will head home for a series against the Atlanta Braves.

Red Sox Looking To Bounce Back

Alex Bregman leads the Red Sox with 51 hits, including a team-high 15 doubles, along with 9 home runs and 31 RBIs, while Rafael Devers has added 45 hits with 12 doubles, 7 home runs and 31 RBIs this season. Trevor Story added 39 hits with 6 home runs, 19 RBIs, and 8 stolen bases, while Jarren Duran has 46 hits with 9 doubles, 4 triples, 2 home runs, 21 RBIs, and a team-high 11 stolen bases. Kristian Campbell added 34 hits with 8 doubles, 4 homers, and 13 RBIs, while Wilyer Abreu has 11 home runs with 27 RBIs and 4 stolen bases, and Ceddanne Rafaela has 2 homers, 2 triples, 15 RBIs, and 7 stolen bases this season.

Why the Boston Red Sox will win

Boston Red Sox Player Prop Facts

Detroit Tigers Recap

The Detroit Tigers come into this game looking to add on to their blowout win over the Red Sox on Monday to improve to 27-15 on the year. After this series, the Tigers will head on the road for a series against the Toronto Blue Jays.

Tigers Looking To Continue Strong Play At Home

Spencer Torkelson has 36 hits along with a .238 batting average, including a team-high 10 home runs, 11 doubles, and 33 RBIs. Kerry Carpenter also has 9 home runs and 21 RBIs, while Riley Greene has 41 hits with 6 doubles, 9 home runs and 24 RBIs, but also has a team-high 48 strikeouts this season. Dillon Dingler has 4 home runs and 16 RBIs, and Zack McKinstry’s added 6 doubles, 3 triples, a home run, and 16 RBIs of his own, along with 36 hits this season. Javier Baez has added 36 hits and 8 doubles as well this season.

Why the Detroit Tigers will win

Detroit Tigers Player Prop Facts

Total Runs Facts

Boston Red Sox vs. Detroit Tigers Prediction

I’m on the Red Sox here. I think it’s worth taking a shot on here with Boston, considering that the Tigers put a whooping on Boston on Monday and now have one of their best options going in Brayan Bello who has looked solid out of the gate and the Red Sox have won all four of his starts so far this season. On the other side, I’m not sure if it’s a bullpen game for the Tigers or if Holton is just an opener, but I don’t love this spot for Detroit, and I think this is Boston’s best shot at a win in this series. Give me the Red Sox here.

Chris Ruffolo's Pick: Boston Red Sox -118

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