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Boston Red Sox vs Cincinnati Reds Prediction 3/28/2026 Today’s MLB Picks

Mar 26, 2026; Cincinnati, Ohio, USA; Boston Red Sox left fielder Roman Anthony (19) scores on a RBI single hit by designated hitter Jarren Duran (not pictured) in the ninth inning against the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

Mar 26, 2026; Cincinnati, Ohio, USA; Boston Red Sox left fielder Roman Anthony (19) scores on a RBI single hit by designated hitter Jarren Duran (not pictured) in the ninth inning against the Cincinnati Reds at Great American Ball Park. Mandatory Credit: Katie Stratman-Imagn Images

MATCHUP Boston Red Sox Cincinnati Reds
Team Records 1-0 0-1
Spread -1.5 113 +1.5 -136
Moneyline -143 +119
Total Over 7.5 (-114) Under 7.5 (-106)
Where Great American Ball Park, Cincinnati, Ohio
When Saturday, March 28, 2026
Time 04:10 PM EDT
TV MLB.TV
The Boston Red Sox and Cincinnati Reds meet Saturday in MLB action at Great American Ball Park. Here’s a Boston Red Sox vs. Cincinnati Reds Prediction. This article will include a Boston Red Sox vs. Cincinnati Reds Pick.

Boston Red Sox Betting Preview


The Boston Red Sox are 1-0 on the year and play the Astros and Padres next. The Boston Red Sox are batting .333 on the season, have a .385 OBP, and have a .361 slugging percentage. The Boston Red Sox pitching staff has a 0.00 ERA and a 0.78 WHIP. Roman Anthony leads the Boston Red Sox with 3 hits and 0 RBI, while Marcelo Mayer and Jarren Duran have combined for 4 hits and 1 RBI.

Sonny Gray gets the ball for the Boston Red Sox, and he was 14-8 with a 4.28 ERA and 201 strikeouts last season. Gray is 1-3 with a 4.18 ERA and 33 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview


The Cincinnati Reds are 0-1 on the year and play the Pirates and Rangers next. The Cincinnati Reds are batting .125 on the season and have a .200 OBP, and a .188 slugging percentage. The Cincinnati Reds pitching staff has a 3.00 ERA and a 1.67 WHIP. Sal Stewart leads the Cincinnati Reds with 3 hits and 0 RBI while Elly De La Cruz and Spencer Steer have combined for 1 hit and 0 RBI.

Brady Singer gets the ball for the Cincinnati Reds, and he was 14-12 with a 4.03 ERA and 163 strikeouts last season. Singer is 2-2 with a 4.88 ERA and 22 strikeouts in his career against the Boston Red Sox.

Why the Cincinnati Reds will win

Why the Boston Red Sox will win

Total Runs Facts

Cincinnati Reds Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Boston Red Sox vs Cincinnati Reds Prediction


It’s one game, but it usually takes the bats time to get going and find a rhythm. The Reds possibly had the worst offensive showing of any team on opening day. No runs, just four hits and 1-7 with runners in scoring position. Gray still has all-star caliber stuff and he’s coming back to Cincinnati, which should make him excited. The Red Sox have a lineup that’s cooking out of the gate. We’re getting a fairly cheap price. I like the Red Sox to get off to a quick 2-0 start.

Randy Chambers's Pick: Boston Red Sox

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