Blue Jays vs Orioles Prediction 9/23/2026 Today’s MLB Picks

In this article we will formulate a Blue Jays vs Orioles prediction for this MLB game on Wednesday, September 23rd at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 77-80 this season after they lost game one by a score of 3-4 on Monday. Toronto scored three runs in the first inning, but they went scoreless over the last eight innings for the loss. The Blue Jays recorded six hits in the game and they were led by Lukes, who went 1-3 with one RBI. Yesavage allowed one hit and one earned run over 2.0 innings, while Roger blew the save and took the loss. Prior to this series, Toronto lost two out of three against the Rangers and two out of three against the Tigers. 

This season, Toronto has a 3.92 ERA with a 1.30 WHIP and a .236 opponent batting average, while they have scored 632 runs with a .248 batting average and a .310 on base percentage. Kazuma Okamoto has led the Blue Jays with 33 home runs and 89 RBIs, while Andres Gimenez has added nine home runs and 58 RBIs. The projected starting pitcher for Toronto in game one is Max Scherzer, who is 3-8 with a 6.07 ERA and a 1.36 WHIP over 72.2 innings pitched this season. The projected starter for game two is TBD. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 76-81 this year after they won game one by a score of 4-3 last night. Baltimore trailed for most of the game, but they got two runs in the eighth to escape with the win. The Orioles recorded six hits in the game and they were led by Alonso, who went 2-4 with two home runs and three RBIs. Baz allowed five hits and three earned runs over 6.2 innings, while Cano got the win and Garcia picked up the save. Prior to this series, Baltimore lost all three against the Brewers, but did win all three against the Mets before that. 

This season, Baltimore has a 4.11 ERA with a 1.34 WHIP and a .252 opponent batting average, while they have scored 697 runs with a .234 batting average and a .314 on base percentage. Pete Alonso has led the Orioles with 40 home runs and 108 RBIs, while Gunnar Henderson has added 24 home runs and 59 RBIs. The projected starting pitcher for Baltimore in game one is Chris Bassitt, who is 8-5 with a 4.64 ERA and a 1.55 WHIP over 97.0 innings pitched this year. The projected starter in game two is TBD.

Why the Baltimore Orioles will win

• The Orioles have won seven of their last eight games at Oriole Park at Camden Yards against AL opponents that held a losing record.
• The Blue Jays have lost four of their last five road games against AL opponents.
• The Orioles have covered the run line in seven of their last eight games at Oriole Park at Camden Yards against AL opponents that held a losing record.
• The Blue Jays have failed to cover the run line in six of their last seven road games against teams that held a losing record.
• The Blue Jays have trailed after 5 innings in four of their last five day games at Oriole Park at Camden Yards against AL opponents.
• The Blue Jays have trailed after 3 innings in three of their last four games at Oriole Park at Camden Yards.

Why the Toronto Blue Jays will win

• The Blue Jays have won each of their last nine day games against AL opponents following a loss.
• The Orioles have lost five of their last six games as home favorites against AL East opponents following a home win.
• The Blue Jays have covered the run line in eight of their last nine games as underdogs against AL opponents following a loss.
• The Orioles have failed to cover the run line in each of their last four day games against AL East opponents.
• The Orioles have trailed after 5 innings in four of their last five games against AL East opponents.
• The Blue Jays have led after 3 innings in six of their last seven games against AL East opponents that held a losing record.

Total Runs Facts

• Seven of the Orioles’ last eight games as favorites against the Blue Jays have gone OVER the total runs line.
• Each of the Blue Jays’ last four games as underdogs have gone OVER the total runs line.
• There has been at least one run scored in the first inning in 13 of Max Scherzer’s last 15 appearances as a starter.
• There has been no run scored during the first inning in six of the Orioles’ last seven games as home favorites against AL East opponents.

Baltimore Orioles Player Prop Facts

• Chris Bassitt has recorded a win in four of his last five appearances with the Orioles as favorites.
• Yohel Pozo has hit a home run in each of his last two appearances with his team as a home favorite against AL opponents.
• Pete Alonso has recorded at least one hit in each of his last 10 Wednesday day appearances against teams that held a losing record.
• Chris Bassitt has recorded four or more strikeouts in each of his last six appearances.

Toronto Blue Jays Player Prop Facts

• Josh Smith has hit a home run in three of his last four road appearances after not playing the previous day.
• Kazuma Okamoto has recorded at least one hit in each of his last 13 appearances with the Blue Jays as underdogs.
• Max Scherzer has recorded five or more strikeouts in 16 of his last 18 appearances against AL East opponents that held a losing record.

Blue Jays vs Orioles Prediction 

Baltimore was able to get the comeback win to start this series on Monday, but they were shutout in the two previous games. The Orioles are 37-42 at home this year, while the Blue Jays are 37-42 on the road. Toronto has also lost three of their last four games and they have scored three runs or fewer in all three of those losses. The Jays are starting Scherzer, who has allowed 1, 6, 3, 0, and 2 earned runs in his last five outings, while Bassitt has allowed 1, 2, 3, 5, and 1 earned run in his last five starts. I am not sure what pitchers will start in either of these games, so I may change my opinion, but I will take the over in game one and the Orioles to win in game two.

David Racey's Pick: Game 1: Over 7 Game 2: Orioles ML