Blue Jays vs Guardians Prediction 9/2/2026 Today’s MLB Picks

In this article we will formulate a Blue Jays vs Guardians prediction for this MLB game on Wednesday, September 2nd at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 68-71 this season after they lost game one by a score of 1-6 on Tuesday night. Toronto led 1-0 in the fifth inning, but they went scoreless over the last four innings in the loss. The Blue Jays recorded three hits in the game and they were led by Kirk, who went 1-4. Miles opened the game, while Arrighetti picked up the loss in relief. Prior to this series, Toronto swept the Mariners in three games, but lost two out of three against the Royals before that. 

This season, Toronto has a 3.96 ERA with a 1.31 WHIP and a .238 opponent batting average, while they have scored 549 runs with a .245 batting average and a .306 on base percentage. Kazuma Okamoto has led the Blue Jays with 28 home runs and 78 RBIs, while Andres Gimenez has added eight home runs and 52 RBIs. The projected starting pitcher for Toronto is Dylan Cease, who is 9-5 with a 2.33 ERA and a 1.05 WHIP over 150.1 innings pitched this season. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 70-68 this year after they won game one by a score of 6-1 last night. Cleveland took the lead in the fifth inning and added two in the seventh and two in the eighth in the win. The Guardians recorded eight hits and they committed one error in the game, while they were led by Martinez, who went 2-3 with one home run and two RBIs. Williams allowed two hits and zero earned runs over 7.0 innings for the win, while Gaddis picked up a hold. Prior to this series, Cleveland lost two out of three against the Royals, but did sweep the Angels before that. 

This season, Cleveland has a 3.70 ERA with a 1.25 WHIP and a .235 opponent batting average, while they have scored 563 runs with a .237 batting average and a .315 on base percentage. Chase DeLauter has led the Guardians with 13 home runs and 60 RBIs, while Angel Martinez has added 14 home runs and 50 RBIs. The projected starting pitcher for Cleveland is Joey Cantillo, who is 9-7 with a 3.70 ERA and a 1.45 WHIP over 136.1 innings pitched this year. 

Why the Cleveland Guardians will win

• The Blue Jays have lost six of their last seven games as favorites against AL Central opponents following a road loss.
• The Guardians have won four of their last five games as underdogs against AL opponents following a home win.
• The Guardians have covered the run line in each of their last 10 Wednesday night games as underdogs against AL opponents.
• The Blue Jays have failed to cover the run line in each of their last five night games against the Guardians following a road loss.
• The Blue Jays have trailed after 5 innings in four of their last five night games against AL Central opponents.

Why the Toronto Blue Jays will win

• The Blue Jays have won 14 of their last 15 games following a loss.
• The Guardians have lost each of their last seven games as underdogs against the Blue Jays following a win.
• The Blue Jays have covered the run line in 10 of their last 11 night games against the Guardians at Progressive Field following a road loss.
• The Guardians have failed to cover the run line in 15 of their last 17 night games at Progressive Field following a home win.
• The Blue Jays have led after 5 innings in 10 of their last 13 games as road favorites.

Total Runs Facts

• Five of the Guardians’ last six night games after playing the previous day have gone UNDER the total runs line.
• Each of the Blue Jays’ last three games have gone UNDER the total runs line.
• There has been no run scored during the first inning in 11 of the Guardians’ last 12 games as underdogs against AL East opponents.
• There has been no run scored during the first inning in four of the Blue Jays’ last five road games against AL opponents.

Cleveland Guardians Player Prop Facts

• Joey Cantillo has recorded five or more strikeouts in each of his last five appearances in night games against teams that held a losing record.
• Angel Martinez has recorded at least one hit in each of his last eight home appearances against opponents that held a losing record.
• Joey Cantillo has recorded a win in each of his last three appearances with the Guardians as home underdogs against AL opponents.
• Angel Martinez has hit a home run in each of his last two appearances.

Toronto Blue Jays Player Prop Facts

• Alejandro Kirk has hit a home run in three of the Blue Jays’ last five night games against opponents that held a winning record.
• Dylan Cease has recorded seven or more strikeouts in each of his last 17 appearances with the Blue Jays as favorites.
• Alejandro Kirk has recorded at least one hit in each of his last 13 appearances in night games against AL teams that held a winning record.
• Dylan Cease has recorded a win in seven of his last eight appearances with the Blue Jays as road favorites.

Blue Jays vs Guardians Prediction 

Cleveland comes into this matchup on a two game winning streak and they have scored 17 runs in those two wins. The Guardians are 33-36 at home this year, while the Blue Jays are 31-36 on the road. Toronto has won three of their last five games and they allowed just four total runs in those three wins. The Blue Jays are starting Cease, who has allowed two earned runs or fewer in four of his last five starts, while Cantillo has allowed two earned runs or fewer in five straight starts. Take the Blue Jays on the road here.

David Racey's Pick: Blue Jays ML