Baltimore Orioles vs Toronto Blue Jays Prediction 9/12/2026 Today’s MLB Picks
Chris Ruffolo
Sep 8, 2026; West Sacramento, California, USA; Toronto Blue Jays first baseman Vladimir Guerrero Jr. (27) catches a line drive against Athletics left fielder Carlos Cortes (not pictured) during the ninth inning at Sutter Health Park. Mandatory Credit: Dennis Lee-Imagn Images
MATCHUP
Baltimore Orioles
Toronto Blue Jays
Team Records
72-76
73-75
Spread
-1.5 155
+1.5 -189
Moneyline
-105
-115
Total
Over 8.5 (-110)
Under 8.5 (-110)
Where
Rogers Centre, Toronto, Ontario
When
Saturday, September 12, 2026
Time
03:07 PM EDT
TV
MLB.TV
The Baltimore Orioles and the Toronto Blue Jays meet Saturday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Baltimore Orioles vs. Toronto Blue Jays prediction.
Starting Pitching Matchup
The Baltimore Orioles will send out Kyle Bradish for the start here and Bradish is 7-13 with a 3.91 ERA and 140 strikeouts this season. Spencer Miles will start for Toronto and is 6-2 with a 2.77 ERA and 81 strikeouts this season.
Baltimore Orioles Recap
The Baltimore Orioles come into this game looking to add on to their 7-4 win over Toronto on Friday to sit at 72-76 this season. After this series, the Orioles will head on the road for a series against the New York Mets.
Orioles Win Back-To-Back Games
Going into Friday, Gunnar Henderson has 126 hits with 25 doubles, 22 home runs and 57 RBIs and Pete Alonso has 147 hits with 24 doubles, 34 home runs and 97 RBIs. Jeremiah Jackson has 54 hits with 10 doubles, 7 home runs and 40 RBIs as well on the year. Samuel Basallo has 76 hits with 10 doubles, 17 home runs and 51 RBIs.
Toronto Blue Jays Recap
The Toronto Blue Jays come into this game looking to bounce back from their loss at the hands of the Orioles on Saturday to slide to 73-75 this season. After this series, Toronto will take on the Detroit Tigers in a series at home.
Blue Jays Lose 4 Of Last 5
Entering Friday, Andres Gimenez has 105 hits with 21 doubles, a triple, 9 home runs and 54 RBIs while Ernie Clement has 148 hits with 30 doubles, 9 home runs and 46 RBIs. Kazuma Okamoto has 120 hits with 23 doubles, 30 home runs, 83 RBIs and a team-high 171 strikeouts while George Springer also has 21 doubles, 14 homers and 48 RBIs. Vladimir Guerrero Jr. has 129 hits with 22 doubles, 8 home runs and 54 RBIs as well. Jesus Sanchez also has 70 hits with 18 doubles, 8 home runs and 35 RBIs.
Baltimore Orioles @ Toronto Blue Jays Betting Trends: September 12, 2026
Probable Starting Pitcher: Spencer Miles Record this season: 6-2 ERA: 2.77
Home Record: 5-1
Last 5 against Orioles: 1-1
Why the Toronto Blue Jays will win
The Blue Jays have won each of their last seven day games following a loss.
The Orioles have lost each of their last six Saturday day road games against AL East opponents.
The Blue Jays have covered the run line in each of their last six games following a home loss.
The Orioles have failed to cover the run line in five of their last six day games against AL East opponents.
The Orioles have trailed after 3 innings in each of their last four day games against AL opponents that held a losing record.
The Orioles have trailed after 5 innings in seven of their last eight Saturday day games.
Probable Starting Pitcher: Kyle Bradish Record this season: 7-13 ERA: 3.91
Road Record: 4-6
Last 5 against Blue Jays: 2-2
Why the Baltimore Orioles will win
The Orioles have won five of their last six games as road underdogs.
The Blue Jays have lost five of their last six games as home favorites against AL East opponents.
The Orioles have covered the run line in each of their last six games as road underdogs.
The Blue Jays have failed to cover the run line in each of their last four games against AL East opponents.
The Blue Jays have trailed after 3 innings in six of their last seven day games against AL opponents that held a losing record.
The Orioles have led after 5 innings in each of their last seven road games against AL opponents.
Total Runs Facts
Each of the last seven games between the Orioles and Blue Jays have gone OVER the total runs line.
Each of the Orioles’ last seven games as underdogs against the Blue Jays have gone OVER the total runs line.
There has been no run scored during the first inning in each of the last five day games between the Orioles and Blue Jays.
There has been no run scored during the first inning in each of the Orioles’ last seven Saturday games against AL East opponents.
Toronto Blue Jays Player Prop Facts
Kazuma Okamoto has hit a home run in three of the Blue Jays’ last four games.
Ernie Clement has recorded at least one hit in each of the Blue Jays’ last 12 day games against AL East opponents that held a losing record.
Baltimore Orioles Player Prop Facts
Coby Mayo has hit a home run in four of his last five road appearances against the Blue Jays.
Coby Mayo has recorded at least one hit in each of his last 10 road appearances.
Kyle Bradish has recorded five or more strikeouts in eight of his last 10 road appearances against AL opponents that held a losing record.
Matchup/League Facts
The Blue Jays rank 30th in the league for triples this season (8).
The Blue Jays rank 30th in the league for walks this season (410).
The Orioles rank 28th in the league for batting average this season (.235).
The Orioles rank 27th in the league for strikeouts against this season (1373).
Baltimore Orioles vs. Toronto Blue Jays Prediction
I’m on Toronto in this one. I just think Toronto is the better team here and while Bradish has had his moments this season, Toronto’s been a lot better against right-handed pitching. I think this series is of the utmost importance to both teams, but I look for the Blue Jays to get some revenge here. Give me Toronto.
