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Baltimore Orioles vs St. Louis Cardinals Prediction 8/27/2026 Today’s MLB Picks

Aug 26, 2026; St. Louis, Missouri, USA; St. Louis Cardinals right fielder Jordan Walker (18) catches a line drive hit by Baltimore Orioles left fielder Dylan Beavers (not pictured) during the fourth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

Aug 26, 2026; St. Louis, Missouri, USA; St. Louis Cardinals right fielder Jordan Walker (18) catches a line drive hit by Baltimore Orioles left fielder Dylan Beavers (not pictured) during the fourth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

MATCHUP Baltimore Orioles St. Louis Cardinals
Team Records 64-68 66-67
Spread -1.5 141 +1.5 -171
Moneyline -120 +100
Total Over 8 (-112) Under 8 (-108)
Where Busch Stadium, St. Louis, Missouri
When Thursday, August 27, 2026
Time 02:15 PM EDT
TV ESPN Unlmtd
The Baltimore Orioles and St. Louis Cardinals meet Thursday in MLB action at Busch Stadium. Here’s a Baltimore Orioles vs St. Louis Cardinals Prediction. This article will include a Baltimore Orioles vs St. Louis Cardinals Pick.

Baltimore Orioles Betting Preview


The Baltimore Orioles are 65-68 on the year and play the Rockies and Athletics next. The Baltimore Orioles are batting .237 on the season, with a .319 OBP and a .399 slugging percentage. The Baltimore Orioles pitching staff has a 4.19 ERA and a 1.34 WHIP. Pete Alonso leads the Baltimore Orioles with 138 hits and 91 RBI, while Leody Taveras and Gunnar Henderson have combined for 199 hits and 100 RBI.

Trevor Rogers gets the ball for the Baltimore Orioles, and he is 9-8 with a 4.14 ERA and 114 strikeouts this season. Rogers is 0-2 with a 3.00 ERA and 15 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 66-68 on the year and play the Pirates and Dodgers next. The St. Louis Cardinals are batting .241 on the season, with a .316 OBP and a .382 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.24 ERA and a 1.34 WHIP. Alec Burleson leads the St. Louis Cardinals with 146 hits and 96 RBI, while Jordan Walker and JJ Wetherholt have combined for 265 hits and 144 RBI.

The St. Louis Cardinals didn’t list a starting pitcher at the time of this writing.

Why the St. Louis Cardinals will win

Why the Baltimore Orioles will win

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Baltimore Orioles Player Prop Facts

Matchup/League Facts

Baltimore Orioles vs St. Louis Cardinals Prediction


The Cardinals and the plus money are worth a look at home with the quick turnaround, but Rogers has looked like his old all-star self over the last two months. Rogers has allowed just 17 earned runs in his last 53.1 innings. The Orioles are 9-2 in Rogers’ last 11 starts. I don’t care who the Cardinals are throwing out there on the mound. The O’s have the edge behind this new and improved Rogers. Give me the Orioles and the soft price.

Randy Chambers's Pick: Baltimore Orioles

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