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Baltimore Orioles vs Kansas City Royals Prediction 4/4/25 MLB Picks

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Kansas City Royals (2-4) vs Baltimore Orioles (3-4)

Game Info: Friday, April 4, 2025 at 7:40 pm (Kauffman Stadium)

The Line: Betting Odds: Kansas City Royals -115 / Baltimore Orioles -105 — Over/Under: 8.5

(Get latest betting odds)

In this article, we will formulate an Orioles vs Royals prediction for this MLB game on Friday, April 4, at Kauffman Stadium in Kansas City, Missouri. Let’s take a look at the prediction for this MLB matchup.

Baltimore Orioles Betting Preview

The Baltimore Orioles (3-4, 2-2 Away) split a four-game series with the Toronto Blue Jays to open a new season, and even though they beat the Boston Red Sox in Game 1 of a three-game series, they lost the following two games. In the latest 8-4 defeat, Charlie Morton suffered his second loss of the year after allowing five runs on six hits with ten strikeouts and two walks in 5.0 innings.

This year, the Orioles average 5.33 runs per game (7th in the MLB) on a .281/.341/.463 triple-slash. When it comes to pitching, the Orioles’ staff has a 4.33 ERA (18th) and 1.40 WHIP (23rd). Cedric Mullins leads the Orioles with a .308 batting average, three home runs, and 11 RBI this season.

Dean Kremer will take the mound for the Orioles on Friday. The 29-year-old righty had an 8-10 record last season in 24 starts with a 4.10 ERA and 1.24 WHIP in 129.2 innings. This season, Kremer is 1-0 with an 8.44 ERA in 5.1  innings.

Kansas City Royals Betting Preview

The Kansas City Royals (2-4, 1-2 Home) lost the opening two series of the season to the Cleveland Guardians and Milwaukee Brewers. The Royals managed to win a game in each of the series, but it seems they should have a better record after losing two of those four games in extra innings. In the most recent 3-2 loss to the Brewers, Cole Ragans was solid through 5.0 innings as he allowed one run on five hits with ten strikeouts and two walks in a no-decision.

This season, the Royals average 3.83 runs per game (17th in the MLB) on a .213/.287/.338 slash line. Regarding pitching, the Royals’ staff has a 3.42 ERA (11th) and 1.31 WHIP (19th). Maikel Garcia leads the Royals with a .353 batting average, two home runs, and three RBI this season.

The projected starting pitcher for the Royals is Seth Lugo, who had a 16-9 record in 33 starts last season with a 3.00 ERA and 1.09 WHIP over 206.2 innings of work. Lugo is 0-0 this season with a 5.40 ERA in 5.0 innings.

Why the Orioles will beat the Royals

Total Runs Facts

Orioles vs Royals Prediction

The Orioles won six of the previous ten H2H encounters, but the Royals were better in three of the last five. Although I appreciate Lugo a bit more than Kremer, I am giving a slight advantage to the Orioles, who hit .286 BA against right-handers, as opposed to the Royals’ .218 BA. Also, Lugo posted a 6.75 ERA in 5.1 innings against Baltimore last year, while Kremer registered a 4.91 ERA in 11.0 innings against Kansas City. It’s going to be a close one, and it could go either way, but I am going with the Orioles in Game 1.

Oliver Zivic's Pick: Orioles ML

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