Baltimore Orioles vs Houston Astros Prediction 8/17/2025 Today’s MLB Picks

Chris Ruffolo

1 month ago

Aug 10, 2025; Baltimore, Maryland, USA; Baltimore Orioles shortstop Gunnar Henderson (2) throws to first for an out during the second inning against the Athletics at Oriole Park at Camden Yards. Mandatory Credit: Daniel Kucin Jr.-Imagn Images

Baltimore (56-67) vs Houston (69-54)

August 17, 2025 at 02:10 PM EDT

The Line: Betting Odds: Houston -125 — Over/Under: +8.5

The Baltimore Orioles and the Houston Astros meet Sunday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Baltimore Orioles vs. Houston Astros prediction.

Starting Pitching Matchup

The Baltimore Orioles will send out Dean Kremer for the start here and Kremer is 8-9 with a 4.17 ERA and 116 strikeouts this season. In his career, Kremer is 3-0 with a 1.82 ERA and 19 strikeouts against Houston. Cristian Javier will get the start for Houston is 1-0 with a 3.60 ERA and 5 strikeouts this season. In his career, Javier is 1-0 with a 1.69 ERA and 22 strikeouts against Baltimore.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to rebound from a 5-4 loss at the hands of the Astros in Saturday’s matchup to sit at 56-67 this season. After this series, the Orioles will head on the road for a series against the Boston Red Sox.

Orioles Have Three-Game Win Streak Snapped

Adley Rutschman has 68 hits with 16 doubles, 9 homers and 27 RBIs. Jackson Holliday has 111 hits with 16 doubles, 2 triples, 14 homers and 45 RBIs. Gunnar Henderson has 121 hits with 29 doubles, 4 triples, 14 home runs and 51 RBIs with 16 stolen bases and 106 strikeouts while Holliday has a team-high 111 strikeouts as well this season. Heston Kjerstad’s added 4 homers and 19 RBIs while Jordan Westburg has 14 home runs and 29 RBIs this season.

Why the Baltimore Orioles will win

The Astros have lost each of their last seven games as favorites against American League opponents following a win.
The Orioles have won four of their last five games as underdogs after playing the previous day.
The Astros have failed to cover the run line each of their last 16 games against American League opponents that held a losing record.
The Orioles have covered the run line in each of their last nine games as underdogs against American League opponents.

Baltimore Orioles Player Prop Facts

Dylan Carlson has hit a home run in three of his four previous appearances at Daikin Park against AL West opponents that held a winning record.
Adley Rutschman has recorded a Double in three of his last four appearances in day games against teams that held a winning record.
Dean Kremer has recorded a win in each of his three previous appearances with the Orioles as underdogs against the Astros.
Dean Kremer has recorded five or more strikeouts in each of his last six appearances against opponents that held a winning record.
Ryan Mountcastle has recorded at least one hit in each of his last nine appearances with the Orioles as underdogs against the Astros.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their win over Baltimore from Saturday’s game to sit at 69-54 this season. After this series, the Astros will take to the road for a series against the Detroit Tigers.

Astros Looking For Series Win

Jose Altuve has 127 hits including 18 doubles, 21 home runs and 63 RBIs. Jeremy Pena also has 115 hits with 20 doubles, 13 homers and 45 RBIs with 17 stolen bases as well. Jake Meyers has 15 doubles as well and Christian Walker has 16 home runs and 65 RBIs but has also accrued a team-high 127 strikeouts so far this season. Altuve also has 8 stolen bases while Jake Meyers has 14 stolen bases this season. Isaac Paredes also has 19 home runs with 50 RBIs of his own and Cam Smith has contributed 7 homers and 48 RBIs.

Why the Houston Astros will win

The Orioles have lost five of their last six games at Daikin Park.
The Astros have won five of their last six home games after playing the previous day.
The Orioles have failed to cover the run line in six of their last seven games against American League opponents after going to extra innings.
The Astros have covered the run line in three of their last four games as home favorites after playing the previous day.

Houston Astros Player Prop Facts

Jose Altuve has hit a home run in four of his last five appearances against the Orioles after playing the previous day.
Cristian Javier has recorded five or more strikeouts in eight of his last nine home appearances against AL opponents that held a losing record.
Isaac Paredes has recorded at least one Double in three of his last four appearances in day games.
Jake Meyers has recorded at least one hit in each of his last 10 appearances against AL opponents.
Cristian Javier has recorded a win in five of his last six appearances in day games against AL teams that held a losing record.
Jeremy Pena ranks 2nd amongst qualified players for Batting Average (.317) this season.

Total Runs Facts

Six of the Orioles’ last seven games as underdogs have gone UNDER the total runs line.
Five of the Astros’ last six home games following an extra innings win have gone UNDER the total runs line.